History, Mission and Vision
|The Cleveland Clinic Center for Reproductive Medicine’s mission is to conduct cutting-edge research into the causes of human reproductive and sexual disorders, leading to the development of new treatments and cures, as well as training of physicians and scientists to advance the understanding of human reproduction, infertility and sexual function.|
|The Cleveland Clinic Center for Reproductive Medicine’s vision is to mentor and train each research fellow, trainee and summer intern using an individualized approach, to develop technical expertise and the ability to work independently.|
|The Cleveland Clinic Andrology Laboratory and Reproductive Tissue Bank is fully accredited by the College of American Pathologists' Reproductive Laboratory Accreditation Program.|
|Click to view accreditation||The ART Training program offered by the Cleveland Clinic Center for Reproductive Medicine is accredited by the American College of Embryology.|
|Scholarship in Teaching Award for the Training Program in Advanced Reproductive Techniques
The Case Western Reserve School of Medicine Scholarship in Teaching Awards is an annual program designed to recognize faculty contribution to education from the preceding year and promote undergraduate, graduate, and continuing medical education teaching as a scholarly activity.
Click here to learn more.
Research @ CRM
The Center for Reproductive Medicine conducts basic science and translational research into oxidative stress, proteomics and male infertility.
For an up to date list of our publications, kindly visit Dr. Agarwal's Research Gate Profile.
A Web of Science Citation Report of Research Publications by the Center for Reproductive Medicine from 1993 to 2013 is available here.
Director, Center of Reproductive Medicine
|Ashok Agarwal, PhD, HCLD (ABB), EMB (ACE)
Dr. Agarwal's h-index is 86 (Google Scholar) and 68 (Web of Science and Scopus), while his citation count is 26,000 on Google Scholar. His RG score is 48.04 on 1364 publications (785 articles, 26 books, 91 chapters and 390 conference papers). Dr. Agarwal is ranked as the #1 Author in Andrology/Male Infertility and ART-related research, based on a Global Ranking of Authors in Andrology or Male Infertility report employing exhaustive searches of the Scopus database. Dr. Agarwal received the 2011 and 2012 Innovator Award for the development of "Remote Sperm Banking Kits" from the Cleveland Clinic Innovations.
Research Coordinator, Center of Reproductive Medicine
|Rakesh Sharma, PhD
Dr. Sharma has published over 190 scientific papers in peer-reviewed scientific journals, authored 30 book chapters, and presented about 360 abstracts at both national and international scientific meetings. He is a recipient of the Merlyn F. Bumpus Junior Investigator Award, Research Excellence Award, Research Fellow of the Year Award, Mentor Recognition Award, Scientist of the Year Award, and Excellence in Male Infertility Research Award.
Supervisor, Andrology Center and Reproductive Tissue Bank
|Sajal Gupta, MBBS, MS, TS (ABB)
Dr. Gupta has published over 60 reviews and research papers in peer-reviewed scientific journals, and authored a dozen book chapters. She has presented about 55 abstracts at both national and international scientific meetings. Dr. Gupta is a recipient of the Award for Highest Productivity in Female Infertility Research, Research Fellow of the Year Award, and Award for Excellence in Female Infertility Research.
Invited Trainers, Clinical Embryologists
|Christina Anagnostopoulou, MS
Christina Anagnostopoulou, M.S. a certified Senior Embryologist by the European Society of Human Reproduction and Embryology (ESHRE). Christina has worked as a clinical embryologist since 2004 and is currently employed at “Embryo ART”, a 500 cycles IVF center in Athens, Greece. She has been an invited faculty for ART training at our Center since 2011.
|Israel Maldonado Ross, MS
Israel Maldonado Rosas has more than 10 years of experience in the field of Assisted Reproduction. He is the first IVF Lab Director of Ingenes with over 2000 cycles per year in México City. In 2011, Isreal introduced, for the first time, blastocyst biopsy and array CGH technology in Mexico. He has been an invited faculty for ART training at our Center since 2013.
Training Program in Assisted Reproductive Techniques (ART)
|Duration:||40 hours (1 week)|
|Duration:||8 hours (1 day)|
General Course Objectives:
- Acquire a basic understanding of assisted reproductive techniques
- Acquire the skills in the use of a micromanipulator
- Impact hands-on training in intracytoplasmic sperm injection
- Acquire skills in various assisted reproductive procedures
- Observe aspiration and retrieval of oocytes
- Participate actively in interactive sessions/lectures
Specific Course Objectives:
- Click on each course name to learn its specific objectives
General Teaching and Learning Methods:
- Fully hands-on, one-to-one laboratory training sessions will be provided under the direct tutelage of 2 highly-competent and practicing Clinical Embryologists
* Module 5 involves training using animal models (frozen hamster oocyte and mouse embryos)
- Other Trainers include Andrologists, Reproductive Endocrinologists and other invited ART experts
- Each training session is customized to the Trainee's
- Professional background
- Level of skill and competence
- Specific training needs
- Desired outcomes obtained from attending the ART training course
- Interactive discussion and teaching sessions
- Live lectures and multimedia presentations in small group sessions
- Four state-of-the-art micromanipulators dedicated solely for training purposes (IVF/ICSI)
- Click on each module to view a sample course syllabus
Aspects of the Training that will be assessed include:
- Knowledge: There will be a summative test comprising multiple choice questions on the practical and theoretical aspects of the ART for each module
- Practical Skills: Each Trainee will be individually tested for competency on specific laboratory techniques learnt during the module
- Presentation and Communication Skills: Each Trainee will be required to give a talk (oral with and without the aid of slides) during the course of the module
Scholarship in Teaching Award
What Each Trainee Will Receive
- Course Syllabus with Reading Material and Lab Protocols
- Free Access to the Cleveland Clinic Alumni Library
- Free Text Book on “Practical Manual of In Vitro Fertilization: Advanced Methods and Novel Devices” edited by Dr. Peter Nagy et al, Springer
- WHO Laboratory Manual for the Examination of Human Semen and Sperm-Cervical Mucus Interaction. 5th Edition (CD)
- Certificate of Training (issued upon successful assessment by the instructor)
- Daily Meal Tickets
Course Evaluation by Past Trainees
Click here to learn more about the evaluation of our training modules by our Past Trainees
Testimonials by Past Trainee
Click here to learn more about what our Past Trainees have to say about their training experience
Information regarding the application procedure is available here.
Online Application Form
Online application forms are available here.
Contact the Course Director
Drop us a line, the Course Director would love to hear from you!
Ashok Agarwal, PhD, HCLD
Assisted Reproduction Training (ART)
Center for Reproductive Medicine
10681 Carnegie Avenue, X11
Cleveland, OH 44195, USA
Tel: (216) 444-9485
Fax: (216) 445-6049
|Clinicians, biologists, scientists and other health professionals with a background and interest in the field of Embryology, Gynecology, Reproductive Medicine, and Andrology are encouraged to apply. Both national and international candidates are welcomed.|
International candidates are encouraged to apply. For specific requirements that may apply to your country, please write to the Program Director, Dr. Ashok Agarwal email@example.com.
Accepted candidates will receive a letter of appointment at the Cleveland Clinic. Foreign nationals will use this letter of appointment to apply for a Visitor B1/B2 Visa at the American Embassy.
Details on past International candidates who have successfully completed the Center for Reproductive Medicine's Assisted Reproduction Training (ART) training program are available here.
|When you apply, we will need to know about your highest academic degree, your specialty, your training objectives, your previous experience in the related area, and your training interests in order to customize your training program.
The following documents are required for your application:
- Recent curriculum vitae/resume
- A letter of recommendation from advisors, teachers, or persons who have first-hand knowledge of you. The following is not acceptable: LORs sent as an e-mail and not printed on official letterhead, not carrying a signature, letters written more than 6-8 weeks before the date of submission.
- Passport size picture
- Copy of passport
|Courses are typically held every year during the Fall months (September and October). Training in selected course modules (except Modules 5 and 6) is available outside these months. In case of questions, reach out to the Program Director, Dr. Ashok Agarwal via: firstname.lastname@example.org.
|Application Opens:||Application Closes:|
|November 1 of the previous year||June 30 of the training year|
|The medium of instruction throughout the training program is in English. Candidates should ideally be able to converse in English with minimum difficulty in order to follow through with the training, assessments and presentations. A TOEFL test score is not required for joining our ART Training Course.|
The current module training fee structure is available here.
Upon acceptance into the program, candidates are required to pay the ART Course Training Fee in full, 8 weeks in advance of their Training Course.
Accepted payment methods of the ART Course Training Fee
- Money Order or Certified Bank Checks
These should be made payable to "Andrology Lab Research Program". Personal checks are not accepted. Money Order or Certified Bank Checks should be mailed by courier (UPS or FedEx) to:
Center for Reproductive Medicine &
Glickman Urological & Kidney Institute
The Cleveland Clinic
10681 Carnegie Ave., X11
Cleveland, Ohio 44195, USA
- Electronic Wire Transfer
Please contact the Program Director (email@example.com) for details of our bank account in Cleveland Clinic.
- Bank Transfer
A levy of $50 will be imposed by our Center to cover the money deducted by the bank during the transfer of funds.
Candidates from outside the United States
The Cleveland Clinic's Center for International Medical Education charges a non-refundable document fee of USD200 for the appointment of foreign-based candidates. This fee may be paid in the form of a Money Order or Certified Bank Check made payable to "Cleveland Clinic Foundation."
Multiple Training Modules
Please note that there is no discount for taking multiple training modules at one go. For example, a candidate taking Module 1A ($950, 1day); Module 1B ($1395, 2 days); Module 2 ($4750, 4 days); Module 3 ($2250, 2 days) and Module 4 ($1950, 1 day) will pay a Course Fee amounting to USD11, 295 and the entire training period will be for 2 weeks).
A refund of 50% of the Course Fee may be allowed upon receipt of written cancellation up to 4 weeks prior to the scheduled training. No refunds will be issued if cancellation is made within 4 weeks of the Training Course.
Ready to Apply?
|Kindly note that all required fields in the online application form must be completed and attachments should be submitted together at the time of application.|
Forward any questions about the course requirements or application process to:
Ashok Agarwal, PhD, HCLD
Assisted Reproduction Training (ART) Center for Reproductive Medicine
10681 Carnegie Avenue, X11
Cleveland, OH 44195, USA
Tel: (216) 444-9485
Fax: (216) 445-6049
How it Works
For a step by step of what to expect once you apply until you begin your training, click here.
How It Works
Interested candidates will submit their application online along with the relevant documents
The Program Director's office will contact the Candidate to set up a phone/video interview* with the Program Director
* the purpose of this interview is to understand the goals and gauge the expectations of the Candidate
The dates of training and payment schedule will be discussed with the accepted candidate and an invoice will be issued
The candidate will then have to deposit the training fee and upon receipt of the fees, a confirmation of training will be issued
The International Center and/or our Center will process the candidate's documentation
In the meantime, the candidate's personalized training schedule will be prepared and information will be sent to the candidate to begin his/her reading to familiarize them with information on the ART Module
Candidates will receive a letter of appointment at the Cleveland Clinic*
*foreign nationals will use this letter of appointment to apply for a Visitor Visa B1/B2 at the American Embassy
Once their training dates and travel plans are confirmed, our Center will help the candidate with their airport transfer and in looking for suitable accommodation while in Cleveland
On the first day, the candidate will undergo a short orientation program, first at the International Center and then at the Andrology Center
This will be followed by the signing of the relevant papers at the Andrology Center
Finally, the candidate will begin their training with our Trainers
The Research and Clinical Laboratories occupy over 5000 square feet of workspace with state-of-the-art instruments and facilities for advanced research in fertility preservation in patients with cancer, proteomics of male and female infertility and molecular markers of oxidative stress and DNA integrity.
|Equipment and Instrumentation|
Instruments available in our facility include: computer assisted semen analyzers, luminometer for oxidative stress measurements, Accuri BD C6 flow cytometer, equipment for western blot, culture room equipped with a sterile hood, several incubators, microscopes, and Narishige micromanipulator fitted on an inverted phase-contrast microscope, spectrophotometers, ELISA plate reader, centrifuges, liquid nitrogen storage tanks, programmable freezers, cold room, etc.
|A large collection of scientific journals, electronic journals/books, and other databases are available through the resourceful Cleveland Clinic Alumni Library.|
Specialized Medical Librarians are ever willing to help in research and use of electronic databases.
Alumni Library Online
Core Research Laboratories
proteomics, metabolomics, genomics, molecular biotechnology, molecular screening, flow cytometry, mass spectrometry, translational research, digital imaging and electron microscopy, etc.
For more information on these core laboratories, visit: http://www.lerner.ccf.org/services
Accommodation in Cleveland
|The city of Cleveland offers a wide variety of accommodation for its visitors. For information on affordable accommodation close by to the Cleveland Clinic, click here.|
Live Trainee Forum (coming soon)