James Young, MD
Dr. Young is Professor of Medicine and Executive Dean, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University and Chairman, Endocrinology and Metabolism Institute. He is also a Physician Director of the Philanthropy Institute, and a founder of the Kaufman Center for Heart Failure. He holds the George and Linda Kaufman Chair. As Study Chairman of the NIH, FDA, and CMS Interagency Registry for Mechanical Circulatory Assist Support (INTERMACS) Dr. Young maintains an active professional role in the fields of heart failure, heart transplant, and MCSD development. He has a joint appointment to the Clinic’s Multi-organ Transplant Center and the Heart and Vascular Institute. Dr. Young is certified as a Diplomat of the American Board of Internal Medicine as well as the subspecialty of Cardiovascular Disease and holds medical licensure from the states of California, Illinois, Ohio, Pennsylvania and Texas.
Dr. Young spent his early years in the San Francisco Bay Area and attended the University of Kansas, where he received his Bachelor of Arts degree with Honors in Biology and was a resident of Stephenson Scholarship Hall. He matriculated to Baylor College of Medicine in Houston, Texas, where he was awarded his Medical Doctor degree with honors in 1974 and elected to Alpha Omega Alpha medical honor society. Dr. Young remained in Houston at the Baylor Affiliated Hospitals to complete his clinical training, joined the faculty, and become a tenured Professor of Medicine 1992. He was the Clinical Coordinator and Scientific Director of Dr. Michael E. DeBakey’s Multi-organ Transplant Center at The Methodist Hospital and Baylor College of Medicine. He relocated to the Cleveland Clinic in 1995 when he became Head of the Section of Heart Failure and Cardiac Transplant Medicine in the Department of Cardiovascular Disease. In 1998 Dr. Young and his surgical colleague, Dr. Patrick McCarthy, created the Kaufman Center for Heart Failure.
Dr. Young’s research activities began during his residency and fellowship when he was a Lipid Research Clinic physician. He subsequently focused his efforts on heart failure, mechanical circulatory support, and cardiac transplant therapeutics including early experiences with dopamine receptor agonists, angiotensin-converting enzyme inhibitors, beta blockers, calcium channel blockers, angiotensin receptor blockers, many new immunosuppressants, and a variety of parenteral inotropes and vasodilators. He has collaborated extensively with his basic science research associates focusing on ‘translational’ research with respect to the molecular biology of cardiac remodeling, allograft arteriopathy, and cardiac allograft rejection. Dr. Young served as the United States of global Principal or Co-Principal Investigator for the HOPE, RESOLVED, SPICE, VMAC, MIRACLE-ICD, RED-HF, ACCLAIM, ONTARGET, TRENSCEND, and CHARM multi-center clinical trials. He has participated in over 150 clinical trials as an investigator. Dr. Young has published over 650 manuscripts and several textbooks. Professionally, Dr. Young is most proud of his contributions to the development and administration of donor organ procurement programs, his efforts to secure recognition for the subspecialty of “Heart Failure and Cardiac Transplant Medicine”, his collaborations with basic and clinical scientists, his contributions to a unique medical school curriculum, and the programs that he helped develop in Houston and Cleveland.