Cleveland Clinic Spin-Off Companies

	ART SARL (Arterial Remodeling Technologies) Technology: Biodegradable polymeric stent. Joint development of CCF and Centre National de la Recherche Scientifique, The University of Montpellier, and University Rene Descartes. Year established: 2002 Stage: Series B (post) Location: France http://www.art-stent.com/
	Autonomic Technologies Technology: Autonomic nervous system stimulation for headache disorders. Year established: 2007 Stage: Series C (post) Location: Palo Alto / Cleveland http://www.autonomictechnologies.com
	Axiomed Spine Corporation Technology: Axiomed is developing the next generation of artificial lumbar disc replacement technology. Although the Company was not founded based on the Cleveland Clinic Technology, Drs. Benzel and Lieberman have been instrumental in helping the Company to refine its technology. Year established: 2001 Stage: Series C (post) Location: Cleveland http://www.axiomed.com Contact Pat McBrayer for more information: PMcBrayer @ axiomed.com
	CardioMEMS Technology: Implantable wireless pressure sensors. Year established: 2000 Stage: Series E (post) Location: Atlanta http://www.cardiomems.com
	CardioNomic Technology: Neurostimulation for cardiac contractility. Year established: 2007 Stage: Pre-Series A Location: Cleveland Contact Jon Heavy, MD for more information: heavyj @ ccf.org
	Clear Catheter Systems Technology: Advanced anti-clogging drainage systems. Year established: 2007 Stage: Pre-Series A Location: Cleveland http://www.clearcatheter.com Contact Ed Boyle, M.D. for more information: emb @ clearcatheter.com
	Cleveland Heart Technology: Artificial heart technologies Year established: 2008 Stage: Series A (post) Location: Cleveland http://www.clevelandheart.com Contact Franz Kellar for more information: : fkellar @ clevelandheart.com
	Cleveland HeartLab, LLC Technology: Cardiovascular diagnostics and specialty reference lab Year established: 2009 Stage: Series A (post) Location: Cleveland http://clevelandheartlab.com Contact Jacob Orville for more information: : jorville @ clevelandheartlab.com
	CleveX Technology: Tissue excision and closure device Year established: 2004 Stage: Series B (post) Location: Columbus http://www.clevex.com
	Congruent Medical Technology: Novel compliant balloon platform technology Year established: 2008 Stage: Pre-Series A Location: Cleveland Contact Sam Kiderman for more information: kiderms @ ccf.org
	Custom Orthopaedic Solutions Technology: Tools to improve orthopaedic surgical outcomes Year established: 2011 Stage: Pre-Seed Location: Cleveland http://www.customorthopaedics.com Contact Pete O'Neill for more information: oneillp2 @ ccf.org
	Enforcer eCoaching Technology: Email-based health and wellness coaching programs Year established: 2011 Stage: Post Series A Location: Cleveland www.youdocs.com Contact Marty Butler for more information: marty@youdocs.com
	Enspire DBS Technology: Deep brain stimulation (DBS) therapy for stroke and traumatic brain injury patients Year established: 2010 Stage: Pre-Seed Location: Cleveland Contact Jon Heavey for more information: heaveyj@ccf.org
	Explorys Technology: Enterprise performance management systems Year established: 2009 Stage: Series C (post) Location: Cleveland http://www.explorys.net Contact Stephen Mchale for more information: stephen.mchale @ explorysmedical.com
	FlexLife Health Technology: Remote patient monitoring tools Year established: 2012 Stage: Pre-Seed Location: Cleveland Contact Roger Richardson for more information: richardsonr@zin-tech.com
	iComet Technologies Technology: Concussion assessment tools Year established: 2011 Stage: Pre-Seed Location: Cleveland Contact Jeff Marshall for more information: marshaj@ccf.org
	ImageIQ Technology: Biomedical imaging and analysis Year established: 2011 Stage: Pre-Series A Location: Cleveland http://www.image-iq.com Contact Tim Kulbago for more information: tkulbago@image-iq.com
	Infuseon Therapeautics Technology: Interactive visual health record Year established: 2012 Stage: Pre-Seed Location: Cleveland Contact David Wang for more information: wangd2@ccf.org
	iVHR Technology: Interactive visual health record Year established: 2012 Stage: Pre-Seed Location: Cleveland Contact Jackie Gerberry for more information: gerberj@ccf.org
	Juventas Therapeutics Technology: Biopharmaceuticals that recruit stem cells to repair ischemic tissue. Year established: 2006 Stage: Series B (post) Location: Cleveland http://www.juventasinc.com Contact Rahul Aras, Ph.D. for more information: rahul @ juventasinc.com
	Merlot Orthopedix Technology: Bone anchorage systems. Year established: 2004 Stage: Pre-Series A Location: Cleveland http://www.merlotorthopedix.com/ Contact Sam Kiderman for more information: kiderms @ ccf.org

NaviGate Cardiac Structures	NaviGate Cardiac Structures Technology: Transcatheter Mitral Valve Year established: 2011 Stage: Pre-Series A Location: Cleveland Contact Mary Kander for more information: kanderm @ ccf.org
	Navis Medical Technology: Steerable guidewire technology. Year established: 2007 Stage: Pre-Series A Location: Cleveland Contact Bill Kolosi for more information: kolosiw @ ccf.org
OptoQuest	OptoQuest Technology: Diagnosis and therapeutic ophthalmic devices Year established: 2008 Stage: Pre-Seed Location: Cleveland Contact Neema Mayhugh, Ph.D. for more information: mayhugn @ ccf.org
	Perfusion Solutions Technology: Heart Pumps Year established: 2008 Stage: Pre-Series A Location: Cleveland Contact Stephan Weber for more information: sweber @ perfsolinc.com
	PeriTec Biosciences Technology: Peritoneum lined peripheral vascular products . Year established:2002 Stage: Pre-Series B Location: Cleveland Contact Timur Sarac, M.D. for more information: saract @ccf.org
	Renovo Neural Technology: Multiple sclerosis therapies Year established: 2008 Stage: Pre-Series A Location: Cleveland http://www.renovoneural.com Contact Satish Medicetty for more information: smedicetty@renovoneural.com
	Rindex Medical Technology: Medical device for cardiovascular diagnostics Year established: 2011 Stage: Pre-Series A Location: California Contact Alex Arrow for more information: alex_arrow@hotmail.com
	SironRX Therapeutics Technology: Wound repair Year established: 2010 Stage: Series A (post) Location: Cleveland http://www.sironrx.com Contact Evan Facher for more information: efacher@sironrx.com

	Tolera Therapeutics Technology: Immune modulation via novel therapies. Year established: 2006 Stage: Series B (post) Location: Cleveland http://www.tolera.com Contact John Puisis for more information: jpuisis @ tolera.com
	ValveXchange Technology: Two-part heart valve including an exchangeable bioprosthetic tissue leaflet set. Year established: 2001 Stage: Pre-Series A Location: Colorado http://www.valvexchange.com Contact Larry Blankenship for more information: lblankenship @ valvexchange.com
YouDocs Beauty	YouDocs Beauty Technology: Social media site for medical, chemical and psychological aspects of human beauty, style and attraction Year established: 2010 Stage: Series A (post) Location: Cleveland http://www.youbeauty.com Contact Jeff Marshall for more information: marshaj @ ccf.org


Exits
	Cleveland BioLabs Technology: Therapeutics for cancer treatment and protection of normal tissues from radiation. Year established: 2003 Stage: NASDAQ Location: Buffalo http://www.cbiolabs.com
	IntElect Medical Technology: GUIDE DBS software application (developed by Cleveland Clinic Lerner Research Institute staff) Year established: 2004 Stage: Acquired 2011 by Boston Scientific for $78 million http://www.intelectmedical.com
Revasc	Revasc Technology: Temporary Endovascular Bypass with Distal Filter Year acquired: 2011 by Micrus Endovascular; which was subsequently acquired by J&J in 2010