Archived Patents

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Back to Top2008 Patents
US7465766: Hydroxyphenyl Cross-Linked Macromolecular Network and Applications Thereof
Inventors: Anthony Calabro, Lee Akst, Daniel Alam, James Chan, Aniq B. Darr, Kiyotaka Fukamachi, Richard A. Gross, David Haynes, Keiji Kamohara, Daniel P. Knott, Hilel Lewis, Alex melamud, Anthony Miniaci, Marchall Strome
Issue Date: 12/16/2008
Brief Description: A dihydroxyphenyl cross-linked macromolecular network used in artificial tissue and tissue engineering applications.

US7463759: System and Method for Vascular Border Detection
Inventors: Jon D. Klingensmith, Anuja Nair, Barry D. Kuban
Issue Date: 12/09/2008
Brief Description: A system and method use the frequency spectrum of a radio frequency (RF) signal backscattered from vascular tissue to identify at least one border on a vascular image.

US7459286: Acessing the Risk of a major Adverse Cardiac Event in Patients with Chest Pain
Inventors: Stanley L. Hazen, Marc S. Penn, Renliang Zhang
Issue Date: 12/02/2008
Brief Description: Methods for characterizing the near term risk of experiencing a major adverse cardiac event in a patient presenting with chest pain.

US7454251: Excess Lead Retaining and Management Desvices and Methods of Using Same
Inventors: Ali R. Rezai, Kenneth B. Baker, John D. hall, Frank G. Shellock
Issue Date: 11/18/2008
Brief Description: A device and method for retaining an excess portion of a lead implanted within or on a surface of a brain of a patient.

US7445620: Apparatus and Method for Protecting Nontarget Tissue of a Patient During Electrocautery Surgery
Inventors: Jon Kefer
Issue Date: 11/04/2008
Brief Description: An apparatus for protecting a nontaret body tissue of a patient during electrocautery surgery.

US7435059: Flow Controlled Blood Pump System
Inventors: William A. Smith, Leonard A. R. Golding
Issue Date: 10/14/2008
Brief Description: A system for pumping blood to assist or assume the cardiac function of a patient is characterized by a blood pump that exhibits a steep performance curve such that only small changes in pump flow occur for large changes in differenctial pressure across the pump.

US7416723: Therapeutic Compositions and Methods useful in Modulating Protein Tyrosine Phosphatases
Inventors: Taolin Yi
Issue Date: 08/26/2008
Brief Description: In one embodiment, a therapeutic composition containing a pentavalent antimonial.

US07407509: Branched Vessel Endoluminal Device with Fenestration
Inventors: Roy K. Greenberg, Karl J. West, Davorin K. Skender, James C. Foster
Issue Date: 08/05/2008
Brief Description: An endoluminal prosthesis comprises a prosthetic trunk comprising a trunk lumen extending therethrought, a wall, an anastomsis in the wall, and a first fenestration in the wall, wherein the prosthetic trunk has a circumference.

US7396360B2: Minimally Invasive Method and Apparatus for Fusing Adjacent Vertebrae
Inventors: Isador H. Leiberman
Issue Date: 07/08/2008
Brief Description: The present invention is a minimally invasive surgical method for fusing adjacent vertebrae.

US7347548B2: Method and Apparatus for Measuring a Retinal Sublayer Characteristic
Inventors: David Huang, Ou Tan, Yan Li
Issue Date: 05/25/2008
Brief Description: Methods and systems are provided for measuring a retinal sublayer characteristic of an eye.

US7378396B2: Therapeutic Agents and Methods for Cardiovascular Disease
Inventors: Stanley L. Hazen, Marc S. Penn
Issue Date: 05/27/2008
Brief Description: The present invention provides methods and agents for treating subjects who have or are at risk of developing or having cardiovascular disease.

US7377938B2: Prosthetic Cardiac Value and Method for Making Same
Inventors: Timur Paul Sarac, Nicholas G. Smedira
Issue Date: 05/27/2008
Brief Description: A prosthetic valve for replacing a cardiac valve includes an expandable support member and at least two valve leaflets.

US7346382B2: Brain Stimulation Models, Systems, Devices, and Methods
Inventors: Cameron C. McIntyre, Christopher R. Butson, John D. Hall, Jaimie M. Henderson
Issue Date: 05/18/2008
Brief Description: This document discusses, amoung other things, brain stimulation models, systems, devices and methods, such as for deep brain stimulation (DBS) or other electrical stimulation.

US7341839B2: Diagnostic Methods for Age Related macular Degeneration
Inventors: Joe G. Hollyfield, Robert G. Salomon, John W. Crabb, Xiaorong Gu
Issue Date: 05/11/2008
Brief Description: Diagnostic methods for identifying a test subject who has or is at risk of developing age-related macular degeneration.

US7368502B2: Hydroxyphenyl Cross-linked Macromolecular Network and Applications Thereof
Inventors: Anthony Calabro, Richard A. Gross, Aniq B. Darr
Issue Date: 05/06/2008
Brief Description: A dihydroxyphenyl cross-linked macromolecular network is provided that is useful in artificial tissue and tissue engineering applications, such as artificial or synthetic cartilage.

US7359554B2: System and Method for Identifying a Vascular Border
Inventors: Jon D. Klingensmith. D. Geoffrey Vince, Anuja Nair, Barry D. Kuban
Issue Date: 04/15/2008
Brief Description: A system and method is provided for using a first vascular image, or more particularly a plurality of control points located thereon, to identify a border on a second vascular image.

US7316689B2: Apparatus for Depositing Bone Grafting Material
Inventors: Isador H. Lieberman
Issue Date: 01/08/2008
Brief Description: An apparatus for depositing bone graft material into a mamalian body comprises a barrel member having an inner surface with internal threads.


Back to Top2007 Patents
CA2424261C: Method and Apparatus for Stabilizing Adjacent Bones
Inventor: Isador Lieberman, M.D.
Issue Date: 12/11/2007
Brief Description: Implant apparatus has a platform with helical spike embedding into each adjacent vertebral bodies to provide a means for fastening.

AU4206815BB: Branched Vessel Endoluminal Device
Inventors: Roy K. Greenberg, M.D., Davorin Skender, James Foster and Karl West
Issue Date: 10/25/2007
Brief Description: Endoluminal prosthesis for repair of damaged vessels has prosthetic branch which is disposed longitudinally along and circumferentially about prosthetic trunk.

US7284442: Method and Apparatus for In Vivo Sensing
Inventors: Aaron J. Fleischman, Ph.D., James R. Talman and Shuvo Roy, Ph.D.
Issue Date: 10/23/2007
Brief Description: Systems and methods for in vivo sensing are provided, involves receiving response signal comprising mix component from in-vivo sensor, and evaluating mix component by system control.

CA2350793C: Rigid Clampable Cannula
Inventor: Ji-Feng Chen
Issue Date: 10/23/2007
Brief Description: Clampable cannula used in conjunction with a ventricle assist device via implantation comprises a rigid layer, a flexible tube coaxial with the rigid layer, and a rigid sleeve.

US7280710: Architecture for Real-Time 3D Image Registration
Inventors: Carlos R. Castro-Pareja, Raj Shekhar and Jogikal M. Jagadeesh
Issue Date: 10/9/2007
Brief Description: Hardware pipeline for brain atlas registration has accumulator/mutual histogram controller operable to send mutual histogram address and control data to mutual histogram RAM, and interpolator sending interpolation weights.

USD552178: Heart Brace
Inventors: Daniel J. Boffa, Eric E. Roselli, M.D., Douglas R. Johnston, M.D., David Nagle, John Robert Mehall, David P. Mason, M.D. and Bruce W. Lytle, M.D.
Issue Date: 10/2/2007
Brief Description: The ornamental design for a heart brace.

DE60129998C0: Apparatus for Implantation into Bone
Inventor: Isador Lieberman, M.D.
Issue Date: 9/27/2007
Brief Description: Apparatus for implantation into bone in a patient's spine or pelvis, e.g. such as bone screws for treating bone fractures.

DE69838097C0: Infectious Clone for Human Parainfluenza Virus Type 3
Inventors: Amiya Banerjee, Ph.D. and Michael A. Hoffman
Issue Date: 8/30/2007
Brief Description: A system for generating recombinant, human parainfluenza virus, particularly infectious, recombinant, human parainfluenza virus type 3 (HPIV-3) is provided.

US7262068: Microneedle Array Module and Method of Fabricating the Same
Inventors: Shuvo Roy, Ph.D. and Aaron Fleischman, Ph.D.
Issue Date: 8/28/2007
Brief Description: Microneedle array module useful for drug delivery, comprises substrate, and microneedles affixed to and protruding outwardly from front surface of substrate.

EP1322242B1: Apparatus for Implantation into Bone
Inventor: Isador Lieberman, M.D.
Issue Date: 8/15/2007
Brief Description: Apparatus for implantation into bone in a patient's spine or pelvis, e.g. such as bone screws for treating bone fractures.

US7074188: System and method of characterizing vascular tissue
Inventors: Ronald Cambron, Francis Vijay, Richard Knight, Delos M. Cosgrove, M.D., Robert C. Foster and Ken Litzie
Issue Date: 7/31/2007
Brief Description: A vacuum-assisted venous drainage reservoir of cardiopulmonary bypass surgery with both hard and soft shell reservoirs.

CA2335851C: Apparatus and Methods for Preparing an Implantable Graft
Inventor: George Muschler, M.D.
Issue Date: 7/24/2007
Brief Description: A kit for preparing an implantable graft, particularly an implantable, composite bone graft is provided.

EP0981537B1: An Infectious Clone for Human Parainfluenza Virus Type 3
Inventors: Amiya Banerjee, Ph.D. and Michael A. Hoffman
Issue Date: 7/18/2007
Brief Description: A system for generating recombinant, human parainfluenza virus, particularly infectious, recombinant, human parainfluenza virus type 3 (HPIV-3) is provided.

CA2426483C: MEMS-Based Integrated Magnetic Particle Identification System
Inventors: Aaron J. Fleischman, Ph.D., Shuvo Roy, Ph.D., Maciej Zborowski, Ph.D. and Jeff Chalmers
Issue Date: 7/3/2007
Brief Description: Particle identification system has substrate with flow channel, magnetic structure with pole pieces for generating magnetic field that acts on magnetic particles and bioferrograph for identifying presence of particles.

DE60313760C0: Neuron Signal Analysis System
Inventor: Erwin B. Montgomery
Issue Date: 6/21/2007
Brief Description: Micro-electrode positioning system for neuron signal analysis, moves micro-electrode to new location, when characteristics of electrical signal data resembles with noise data characteristics.

US7223552: Myeloperoxidase, A Risk Indicator for Cardiovascular Disease
Inventors: Renliang Zhang, M.D., Ph.D. and Stanley Hazen, M.D., Ph.D.
Issue Date: 5/29/2007
Brief Description: Diagnostic test for identifying a human patient's risk of developing or having cardiovascular disease by comparing levels of myeloperoxidase activity, myeloperoxidase mass in bodily sample with predetermined values.

AU2249893BB: Myeloperoxidase, A Risk Indicator for Cardiovascular Disease
Inventors: Renliang Zhang, M.D., Ph.D. and Stanley Hazen, M.D., Ph.D.
Issue Date: 5/24/2007
Brief Description: Diagnostic test for identifying a human patient's risk of developing or having cardiovascular disease by comparing levels of myeloperoxidase activity, myeloperoxidase mass in bodily sample with predetermined values.

EP1492449B1: Neuron Signal Analysis System
Inventor: Erwin B. Montgomery
Issue Date: 5/9/2007
Brief Description: Micro-electrode positioning system for neuron signal analysis, moves micro-electrode to new location, when characteristics of electrical signal data resembles with noise data characteristics.

US7215802: System and Method for Vascular Border Detection
Inventors: Jon D. Klingensmith, Anuja Nair, Ph.D., Barry D. Kuban and D. Geoffrey Vince, Ph.D.
Issue Date: 5/8/2007
Brief Description: Intra -vascular ultrasound image border identifying method for use by clinician, involves identifying two portions of transformed RF data that corresponds to blood and non-blood portion of vascular tissue respectively.

CA2424173C: Apparatus for Implantation into Bone
Inventor: Isador Lieberman, M.D.
Issue Date: 4/17/2007
Brief Description: Apparatus for implantation into bone in a patient's spine or pelvis, e.g. such as bone screws for treating bone fractures.

US7183256: TIMP3 as VEGF Inhibitor
Inventor: Bela Anand-Apte, M.D., Ph.D.
Issue Date: 2/27/2007
Brief Description: New polypeptide comprising a portion of the C-terminal domain of tissue inhibitor of metalloproteinase 3 which inhibits binding of VEGF to VEGFR2, useful for treating angiogenic disease.

US7182736: Apparatus and Method for Assessing Loads on Adjacent Bones
Inventors: Shuvo Roy, Ph.D., Aaron Fleischman, Ph.D., Edward C. Benzel, M.D. and Lisa Ferrara
Issue Date: 2/27/2007
Brief Description: Apparatus for use to assess loads on adjacent bones comprises a body for insertion between adjacent bones, load sensor and a telemetric device coupled with the sensor.

US7181288: Neuromodulation Device and Method of Using the Same
Inventors: Ali R. Rezai, M.D., John D. Hall, Barry D. Kuban and Ken Baker, Ph.D.
Issue Date: 2/20/2007
Brief Description: Device for modulating volume of neural tissue, has leads radially constrained within lumen coupled to actuator mechanism and deploys radially outwardly into neural tissue.

US7175597: Non-Invasive Tissue Characterization System and Method
Inventors: D. Geoffrey Vince, Ph.D., Anuja Nair, Ph.D. and Jon D. Klingensmith
Issue Date: 2/13/2007
Brief Description: Plaque composition determining system for physicians that has correlation logic that associates signal properties to pre-determined signal properties of plaque components and identifies components of blood vessel based on association.

US7172874: Diagnostic Methods for Age Related Macular Degeneration
Inventors: Joe G. Hollyfield, Ph.D., Robert G. Salomon, Ph.D., John W. Crabb, Ph.D. and Xiaorong Gu
Issue Date: 2/6/2007
Brief Description: Diagnosing disease associated with oxidation of docosahexaenoic acid containing lipids in test subject, by detecting presence of elevated level of 2-(omega-carboxyethyl) pyrrole adducts in bodily fluid obtained from test subject.

US7169106: Intraocular Pressure Measurement System Including a Sensor Mounted in a Contact Lens
Inventors: Aaron J. Fleischman, Ph.D. Shuvo Roy, Ph.D. and Hilel Lewis, M.D.
Issue Date: 1/30/2007
Brief Description: Intraocular pressure measurement system used for glaucoma patients, includes contact lens, and sensor comprising contact surface including outer non-compliant region and inner compliant region, and region of conductive material.

US7168116: Patient Support Apparatus Having an Air Cell Grid and Associated Method
Inventors: Steven L. Reger, Ph.D. and Richard R. Navarro
Issue Date: 1/30/2007
Brief Description: An apparatus for supporting a patient during a medical procedure. The apparatus has a bead bag when subjected to vacuum, becomes rigid for supporting air cell grid against patient to maximize surface area of contact between patients and apparatus.

DE69836487C0: Minimally invasive cardiac surgery procedure
Inventor: Delos M. Cosgrove, M.D.
Issue Date: 1/4/2007
Brief Description: Method of performing a minimally invasive cardiac surgery on a patient, eg. aortic valve replacement, includes making a parasternal incision across a predetermined number of costal cartilage, and exercising one or more costal cartilage to provide access to portion of the heart.

CA2424520C: Microneedle Array Module and Method of Fabricating the Same
Inventors: Aaron Fleischman, Ph.D. and Shuvo Roy, Ph.D.
Issue Date: 1/2/2007
Brief Description: Microneedle array module useful for drug delivery, comprises substrate, and microneedles affixed to and protruding outwardly from front surface of substrate


Back to Top2006 Patents
US7087079: Method and apparatus for replacing a mitral valve with a stentless bioprosthetic valve
Inventors: Jose L. Navia, M.D., Jose A. Navia, M.D., Jorge Jordana, M.D.
Issue Date: 8/8/2006
Brief Description: The present invention is a stentless bioprosthetic valve for replacing a native mitral valve resected from a valve annulus in a heart. The bioprosthetic valve comprises at least one piece of biocompatible material comprising a bi-leaflet conduit having dimensions that correspond to the dimensions of the native mitral valve.

US7074188: System and method of characterizing vascular tissue
Inventors: Anuja Nair, Ph.D., D. Geoffrey Vince, M.D., Jon D. Klingensmith, Barry D. Kuban
Issue Date: 7/11/2006
Brief Description: The present invention provides a system and method of using backscattered data and known parameters to characterize vascular tissue. Embodiments of the present invention operate in accordance with an ultrasonic device and a computing device comprising a characterization application and a database.

US7048856: Ultrafiltration membrane, device, bioartificial organ, and methods
Inventors: William H. Fissell, IV, H. David Humes, Shuvo Roy, Ph.D. Aaron Fleischman, Ph.D.
Issue Date: 5/23/2006
Brief Description: The present invention relates to ultrafiltration. In particular, the present invention provides a compact ultrafiltration device and methods for generating an ultrafiltrate, both of which can be used for a variety of applications, including, but not limited to filtering blood, diagnostic applications, and as a bioreactor. The present invention also provides bioartificial organs.

  DE69930257C0: Apparatus and methods for preparing an implantable graft
Inventors: George F. Muschler, M.D.
Issue Date: 5/4/2006
Brief Description: A kit for preparing a composite bone graft from a bone marrow aspirate suspension.

US7014653: Furcated Endovascular Prosthesis
Inventors: Kenneth Ouriel, M.D., Daniel Clair, M.D.
Issue Date: 3/21/2006
Brief Description: An endovascular prosthesis that can be anchored within the vascular tissue and can be useful in treating aortic aneurysm.

  KR 10-0564716: Apparatus and Methods for Preparing an Implantable Graft
Inventors: George F. Muschler, M.D.
Issue Date: 3/21/2006
Brief Description: A kit for preparing a composite bone graft from a bone marrow aspirate suspension.

US7011681: Bioprosthetic Cardiovascular Valve System
Inventors: Ivan Vesely, Ph.D.
Issue Date: 3/14/2006
Brief Description: A cardiovascular valve system including a permanent base unit that is affixed to the patient using conventional sutures or staples, and a collapsible valve having a collapsible frame that mates with the permanent base unit.

EP1085842B1: Apparatus and Methods for Preparing an Implantable Graft
Inventor: George Muschler, M.D.
Issue Date: 3/8/2006
Brief Summary: A kit for preparing a composite bone graft from a bone marrow aspirate suspension.

US7004926: Apparatus and Method for Auto-Retroperfusion of a Coronary Vein
Inventors: Jose L. Navia, M.D., Jose A. Navia, M.D., Jorge Jordana, M.D.
Issue Date: 2/28/2006
Brief Description: Apparatus for automatically retroperfusing the coronary vein with oxygenated blood from artery with an occluding structure for decreasing back-flow of blood into right atrium.

  AU2002236549: Catheter for Removal of Solids from Surgical Drains
Inventors: John Liddicoat, A. Marc Gillinov, Mark S. Goodin, Bryan Byerman
Issue Date: 2/24/2006
Brief Description: Catheter for removal of solids from surgical drains using adapter with one way check valve.

US6994672: Apparatus and Method for Measuring Intraocular Pressure
Inventors: Aaron Fleischman, Ph.D., Shuvo Roy, Hilel Lewis, M.D.
Issue Date: 2/7/2006
Brief Description: Intraocular pressure measuring device, has sensor with contact surface having inner compliant region with impedance element coupled to conductive material, so that impedance element is energized with respect to the external signal.

  DE60025170C0: Diagnostic Methods for Asthma
Inventors: Stan Hazen, M.D., Ph.D., Weikia Wu, David Schmitt
Issue Date: 2/2/2006
Brief Summary: Diagnosing and prognosing diseases associated with the activation of eosinophils, e.g. asthma.

US6982298: Hydroxyphenyl Cross-Linked Macromolecular Network and Applications Thereof
Inventors: Anthony Calabro, Ph.D., Richard Gross, M.D., Aniq Darr
Issue Date: 1/3/2006
Brief Description: A cross linked macromolecular network that is useful in artificial tissue and tissue engineering applications such as synthetic cartilage.


Back to Top2005 Patents
EP1159614B1: Diagnostic Methods for Asthma
Inventors: Stan Hazen, M.D., Ph.D., Weikia Wu, David Schmitt
Issue Date: 12/28/2005
Brief Description: Diagnosing and prognosing diseases associated with the activation of eosinophils, e.g. asthma.
US6953462: Apparatus for Implantation into Bone
Inventor: Isador Leiberman, M.D.
Issue Date: 10/11/2005
Brief Description: An implantable bone anchor that is resistant to toggling and being pulled from the bone. The anchor includes helical spikes that extend from the surface of the anchor and are engagable with the bone.

  DE60111508C0: Ventricular Assist System Secondary Impeller
Inventors: David Horvath, Leonard Golding, M.D. William Smith
Issue Date: 7/21/2005
Brief Description: Cardiac assisting device has blood pumped from inlet to outlet by a primary impeller with a secondary impeller preventing blood stagnation.

US6911916: Method and Apparatus for Accessing Medical Data Over a Network
Inventors: Gang Wang, Joseph Hahn, M.D., Amante Mangaser, David Roe, Charles Steiner, Darrin Uecker
Issue Date: 6/28/2005
Brief Description: A single interface data retrieval method for accessing many disparate forms of medical data over a local area network, wide area network or direct connection.

  DE60020257C0: Continuous Particle and Molecule Separation with an Annular Flow Channel
Inventors: Maciej Zborowski, Ph.D. Jeff Chalmers, Lee Moore
Issue Date: 6/23/2005
Brief Description: Annular separation channel for use in separating particles, e.g. metals, includes two sequential spaces respectively bonded to cylindrical walls, and third space partially bound by two walls.

EP1267959B1: Ventricular Assist System with Secondary Impeller
Inventors: David Horvath, Leonard Golding, M.D. William Smith
Issue Date: 6/15/2005
Brief Description: Cardiac assisting device has blood pumped from inlet to outlet by a primary impeller with a secondary impeller preventing blood stagnation.

EP1224023B1: Continuous Particle and Molecule Separation with an Annular Flow Channel
Inventors: Maciej Zborowski, Ph.D. Jeff Chalmers, Lee Moore
Issue Date: 5/18/2005
Brief Description: Annular separation channel for use in separating particles, e.g. metals, includes two sequential spaces respectively bonded to cylindrical walls, and third space partially bound by two walls.

US6884591: Peripheral Marker of Blood Brain Barrier Permeability
Inventors: Damir Janigro, Ph.D., Marc Mayberg, M.D., Gene Barnett, M.D.
Issue Date: 4/26/2005
Brief Description: Detection of blood brain barrier permeability for diagnosing diseases such as neuronal distress. The method comprises detecting levels of S100 beta protein in blood samples and compares the result to control levels.

US6885888: Electrical Stimulation of the Sympathetic Nerve Chain
Inventor: Ali Rezai, M.D.
Issue Date: 4/26/2005
Brief Description: Method affects physiological disorders by stimulating specific locations on the sympathetic nerve chain via an electrode adjacent or in communication with ganglions on the nerve chain.

  ZA0402461A: Skin Lesion Exciser and Skin-Closure Device Therefor
Inventors: Michael Banbury, M.D., Jillian Banbury, M.D.
Issue Date: 3/29/2005
Brief Description: Skin lesion exciser for excising skin tags, moles, lesions and other discrete patches of skin from humans or animals, has moving engagement portion and blade for excising lesion simultaneously as skin is closed by closure device.


Back to Top2004 Patents
DE60107401C0: Chronic Performance Control System for Rotodynamic Blood Pumps
Inventors: Alexander Medvedev, Ph.D., Leonard Golding, M.D., and Alexander Massiello
Issue Date: 12/30/2004
Brief Description: Cardiac assist apparatus chronic performance control system for rotodynamic blood pump has controller directing power to drive unit in response to sensed current, voltage and rotational frequency waveforms.

  DE69827266C0: System and Method for Minimally Invasive Surgery with Vacuum-Assisted Venous Drainage
Inventors: Delos M. Cosgrove, M.D., Robert C. Foster, Ronald Cambron, Francis Vijay, Richard Knight, and Ken Litzie
Issue Date: 12/2/2004
Brief Description: The present invention relates generally to a reduced prime volume cardiopulmonary bypass system that is useful in connection with minimally invasive cardiovascular surgical procedures, and more specifically, vacuum-assisted venous drainage systems and associated minimally invasive surgical methods.

  EP1267958B1: Chronic Performance Control System for Rotodynamic Blood Pumps
Inventors: Alexander Medvedev, Ph.D., Leonard Golding, M.D., and Alexander Massiello
Issue Date: 11/24/2004
Brief Description: Cardiac assist apparatus chronic performance control system for rotodynamic blood pump has controller directing power to drive unit in response to sensed current, voltage and rotational frequency waveforms.

US6810753: Displacement Transducer
Inventors: Antonio Valdevit, Helen Kambic, Theodore Elster, and Ahmed El-Said
Issue Date: 11/2/2004
Brief Description: A measurement device capable of measuring very tiny strains on the order of 100 µm or less, with a resolution of at least 10 µm in both the positive and negative direction.

  EP1003575B1: System for Minimally Invasive Surgery with Vacuum-Assisted Venous Drainage
Inventors: Delos M. Cosgrove, M.D., Robert C. Foster, Ronald Cambron, Francis Vijay, Richard Knight, and Ken Litzie
Issue Date: 10/27/2004
Brief Description: The present invention relates generally to a reduced prime volume cardiopulmonary bypass system that is useful in connection with minimally invasive cardiovascular surgical procedures, and more specifically, vacuum-assisted venous drainage systems and associated minimally invasive surgical methods.

US6802806: Apparatus for Use with an Inflow Cannula of Ventricular Assist Device
Inventors: Patrick M. McCarthy, and Ji-Feng Chen
Issue Date: 10/12/2004
Brief Description: Conduit assembly used with inflow cannula for directing blood flow from heart to ventricular assist device (VAD). Assembly has connecting nuts which individually couple opposite ends of conduit to corresponding portions of inflow cannula.

  AU0777200B2: Continuous Particle and Molecule Separation with an Annular Flow Channel
Inventors: Maciej Zborowski, Ph.D., Jeff Chalmers, and Lee R. Moore
Issue Date: 10/7/2004
Brief Description: Annular separation channel for use in separating particles, e.g. metals, includes two sequential spaces respectively bonded to cylindrical walls, and third space partially bound by two walls.

US6800087: Blanket System for Temperature Regulation of a Patient
Inventors: Francis A. Papay, M.D., and Stefan Budac
Issue Date: 10/5/2004
Brief Description: Blanket system maintains patient body temperature before, during, and after both surgical and non-surgical procedures. System includes cover blanket and air blower/vacuum system.

US6798199: Method for Synchronizing Magnetic Resonance Imaging Data to Body Motion
Inventors: Andrew C. Larson, M.D. Orlando P. Simonetti, Richard D. White, and Gerhard Laub.
Issue Date: 9/28/2004
Brief Description: Magnetic resonance images are synched to patient motion (beating heart, expanding lungs, etc.) by extracting timing information directly from the MR image data rather than collecting additional timing data.

  AU0776527B2: Intravascular Ultrasonic Analysis Using Active Contour Method and System
Inventors: Jon D. Klingensmith, David Geoffrey Vince, M.D., and Raj Shekhar
Issue Date: 9/16/2004
Brief Description: Determining boundary contour of blood vessel by displaying ultrasound images, selecting control points on boundary, and interpolating between control points to generated boundary contour.

US6790372: Microneedle Array Module and Method of Fabricating the Same
Inventors: Shuvo Roy, Ph.D., and Aaron J. Fleischman, Ph.D.
Issue Date: 9/14/2004
Brief Description: Microneedle array module useful for drug delivery, comprises substrate and microneedles affixed to and protruding outwardly from front surface of substrate.

  DE69825150C0: Rotodynamic Pump with Non-Circular Hydrodynamic Bearing Journal
Inventors: Leonard Golding, M.D., and William Smith
Issue Date: 8/26/2004
Brief Description: Rotodynamic pump with non-circular hydrodynamic bearing journal, suitable for use as heart or blood pumps or as ventricular assist devices.

  EP0968369B1: Rotodynamic Pump with Non-Circular Hydrodynamic Bearing Journal
Inventors: Leonard Golding, M.D., and William Smith
Issue Date: 7/21/2004
Brief Description: Rotodynamic pump with non-circular hydrodynamic bearing journal, suitable for use as heart or blood pumps or as ventricular assist devices.

US6762038: Mutant Cell Lines and Methods for Producing Enhanced Levels of Recombinant Proteins
Inventors: Robert H. Silverman, Ph.D., Bryan R. G. Williams, Fulvia Terenzi, Aimin Zhou, and Sandy Der
Issue Date: 7/13/2004
Brief Description: New isolated mutant mouse cell having a homozygous disruption in the RNase L and PKR genes for producing high levels of exogenous, recombinant protein such as may be used in protein therapeutics.

US6755813: Apparatus and Method for Performing Thrombolysis
Inventors: Kenneth Ouriel, M.D., Harry B. Goodson, and Roy K. Greenberg, M.D.
Issue Date: 6/29/2004
Brief Description: Invention performs thrombolysis by introducing an infusate into the lumen via catheter with a series of infusion ports spaced axially along the length of the infusion portion of the catheter.

US6752986: Composition and Methods for Affecting Metallocorrinoid Uptake
Inventors: Joseph A. Bauer, Ph.D., and Daniel J. Lindner, M.D., Ph.D.
Issue Date: 6/22/2004
Brief Description: Invention enhances uptake and availability of metallocorrinoids which is useful in the prevention of conditions resulting from low expression or activity of proteins and other conditions that benefit from enhanced metallocorrinoid uptake.

US6749619: Apparatus and Method for Eliminating Dislodged Thrombus
Inventors: Kenneth Ouriel, M.D., Harry B. Goodson, and Roy K. Greenberg, M.D.
Issue Date: 6/15/2004
Brief Description: Apparatus for eliminating dislodged thrombus in a blood vessel. Apparatus has catheter having infusion ports which deliver thrombolytic fluid to dissolve dislodged thrombus trapped in filter.

US6749568: Intraocular Pressure Measurement System Including a Sensor Mounted in a Contact Lens
Inventors: Aaron J. Fleischman, Ph.D., Shuvo Roy, Ph.D., Hilel Lewis, M.D.
Issue Date: 6/15/2004
Brief Description: Intraocular pressure measurement device fabricated from a contoured contact lens and using telemetry to send output signals.

US6732739: Minimally Invasive Cardiac Surgery Procedure
Inventors: Delos M. Cosgrove, M.D.
Issue Date: 5/11/2004
Brief Description: Method of performing a minimally invasive cardiac surgery on a patient (e.g. aortic valve replacement). Method includes making a parasternal incision across a predetermined number of costal cartilage and exercising one or more costal cartilage to provide access to portion of the heart.

US6723131: Composite Bone Marrow Graft Material with Method and Kit
Inventors: George F. Muschler, M.D.
Issue Date: 4/20/2004
Brief Description: A composite bone marrow graft material derived from non-anticoagulated bone marrow aspirate which improves graft efficacy and method for preparing the graft material.

US6725081: Intravascular Radiation Delivery Device
Inventors: Jay P. Ciezki, M.D., Eugene J. Jung, Jr., Eric J. Lee, Emin M. Tuzcu, M.D., James D. Savage, and Martin S. Weinhous, Ph.D.
Issue Date: 4/20/2004
Brief Description: Precision method for delivering radiation dosage to a blood vessel site via adjustable catheter.

US6706005: Apparatus and Method for Assessing Loads on Adjacent Bones
Inventors: Shuvo Roy, Ph.D., Aaron J. Fleischman, Ph.D., Edward C. Benzel, M.D., and Lisa Ferrara
Issue Date: 3/16/2004
Brief Description: Micro-Electro-Mechanical Systems (MEMS) sensor that monitors the loads on adjacent bones in vivo remotely via telemetry.

US6703632: Radiation Shield
Inventors: Roger M. Macklis, M.D., Jason Sohn, and Twyla Willoughby
Issue Date: 3/9/2004
Brief Description: A shape conforming radiation shield, provided with safety dosimeters and a fail-safe system, for patients undergoing radiotherapy treatment.

US6689168: Method and Apparatus for Stabilizing Adjacent Bones
Inventors: Isador H.Lieberman, M.D.
Issue Date: 2/10/2004
Brief Description: A bone screw with helically-shaped spikes for stabilizing vertebral bodies while they fuse together.

US6687422: Discrete Image Data Interpolation using Sub-Unity Shift
Inventors: Qin-Sheng Chen, Ph.D. and Martin S. Weinhous, Ph.D.
Issue Date: 2/3/2004
Brief Description: Digital image interpolation method useful for medical imaging such as computer tomography and magnetic resonance imaging.

US6682537: Apparatus and Method for Capturing a Wire in a Blood Vessel
Inventors: Kenneth Ouriel, M.D., and Daniel Clair, M.D.
Issue Date: 1/27/2004
Brief Description: A tube apparatus for capturing a wire within a lumen of a blood vessel; also includes ability to constrict wire loop.

US6682490: Apparatus and Method for Monitoring a Condition Inside a Body Cavity
Inventors: Shuvo Roy, Ph.D., Kenneth Ouriel, M.D., and Aaron Fleischman, Ph.D.
Issue Date: 1/27/2004
Brief Description: Micro-Electro-Mechanical Systems (MEMS) sensor to monitor conditions inside a body cavity, such as AAA, remotely via telemetry.