Chorioamnionitis

Chorioamnionitis is a condition that can affect pregnant women. In this condition, bacteria infects the chorion and amnion (the membranes that surround the fetus) and the amniotic fluid (in which the fetus floats). This can lead to infections in both the mother and fetus. In most cases, this may mean the fetus has to be delivered as soon as possible.

What are the causes of chorioamnionitis?

Chorioamnionitis is caused by a bacterial infection that usually starts in the mother's urogenital tract. Specifically, the infection can start in the vagina, anus, or rectum and move up into the uterus where the fetus is located.

Chorioamnionitis occurs in up to 2 percent of births in the United States and is one of the causes of premature delivery.

What are the risk factors for chorioamnionitis?

Certain factors might create a higher risk for chorioamnionitis, including:

What are the symptoms of chorioamnionitis?

Although chorioamnionitis does not always cause symptoms, some women with the infection might have the following:

How is chorioamnionitis diagnosed?

Chorioamnionitis is most often diagnosed by physical exam and the findings listed above. Other clues can be found by taking a blood sample from the mother and checking for bacteria. In addition, the doctor might take samples of the amniotic fluid to look for bacteria. The doctor might also use ultrasound to check on the health of the fetus.

How is chorioamnionitis treated?

If your doctor diagnoses chorioamnionitis, he or she may treat you with antibiotics to help to treat the infection. However, often the treatment is to deliver the fetus. In addition, if the newborn has an infection, he or she will be given antibiotics, as well.

What are the complications of chorioamnionitis?

If the mother has a serious case of chorioamnionitis, or if it goes untreated, she might develop complications, including:

The newborn might also have complications from a bacterial infection, including sepsis (infection of the blood), meningitis (infection of the lining of the brain and the spinal cord), and respiratory problems.

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This information is provided by the Cleveland Clinic and is not intended to replace the medical advice of your doctor or health care provider. Please consult your health care provider for advice about a specific medical condition. For additional health information, please contact the Center for Consumer Health Information at the Cleveland Clinic (216) 444-3771 or toll-free (800) 223-2273 extension 43771. If you prefer, you may visit www.clevelandclinic.org/health/ or www.clevelandclinicflorida.org. This document was last reviewed on: 10/18/2012

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