Normal Pressure Hydrocephalus

The term hydrocephalus comes from the Greek "hydro," meaning "water," and "cephalus," meaning "head." Hydrocephalus, then, is an abnormal accumulation of water-like fluid in the head. The fluid, called cerebrospinal fluid (CSF), is made in the spaces of the brain called ventricles. CSF circulates around the brain and spinal cord (the central nervous system), cushioning and protecting the delicate tissues. CSF also maintains the balance of nutrients to the brain and spinal cord and removes waste products.

Every day, the body makes about 8 oz. of CSF, and about the same amount of fluid is reabsorbed into the bloodstream. Hydrocephalus occurs when there is an imbalance between the amount of CSF produced and the amount absorbed. This imbalance can be caused by a blockage that interferes with the flow of CSF around the brain and spinal cord. This is called obstructive or non-communicating hydrocephalus. Hydrocephalus can also result from an overproduction of CSF or the underabsorption of CSF into the bloodstream. This is called communicating hydrocephalus.

Most cases of hydrocephalus are present at birth. This is called congenital hydrocephalus. Cases that develop later in life are called acquired. Many factors can contribute to acquired hydrocephalus, including head injury, stroke, tumor, and meningitis, which is an infection of the membranes (meninges) that surround the brain and spinal cord. When the absorption of CSF is blocked, the CSF begins to accumulate in the ventricles of the brain, causing the ventricles to become enlarged and increasing pressure inside the head.

What is normal pressure hydrocephalus?
Normal pressure hydrocephalus, or NPH, is an acquired hydrocephalus that most often occurs in people over age 60. NPH is different from typical hydrocephalus in that it may not cause an obvious increase of pressure in the head, but may have fluctuations in CSF pressure from high to normal to low.

What are the symptoms of NPH?
There are three classic symptoms of NPH. They are referred to as the classic triad of symptoms:

Most patients with NPH do not have headaches, which are common in patients with obstructive hydrocephalus. 

What causes NPH?
Many cases of NPH have no known cause. Some cases of NPH are linked to bleeding in the brain or a blockage in CSF flow through and around the brain and spinal cord. It is believed that blockages are linked to a history of infection, stroke, or head injury.

How common is NPH?
Because the symptoms of NPH are similar to those of other diseases, people with NPH are often diagnosed with disorders such as Alzheimer's or Parkinson's disease, or the symptoms may be attributed to the aging process. For that reason, it is difficult to know how many people actually have NPH. However, it is estimated that as many as 10 percent of people with dementia attributed to other disorders may actually have NPH.

How is NPH diagnosed?
A careful review of symptoms, a medical history, and various tests are used to diagnose NPH. Tests used may include:

How is NPH treated?
NPH may be treated using an implantable shunt to drain excess CSF away from the brain and spinal cord.

What complications are linked to NPH treatment?
Complications of NPH treatment are those associated with any surgical procedure. They include bleeding, infection, and reaction to the anesthesia used during surgery. Patients might also experience mild abdominal pain. Seizures also may occur as surgery on the brain can affect very sensitive areas of the brain. Fortunately, these complications are not common, and in most cases can be successfully treated.

What is the outlook for people with NPH?
With treatment, the symptoms of NPH can be partially or even fully reversible. On the other hand, the outlook is poor when the disorder is not treated appropriately. Without treatment, the symptoms can continue to worsen and lead, eventually, to death.

Is there any way to prevent NPH?
Right now, there is no known way to prevent NPH. However, getting treatment as soon as symptoms appear can improve those symptoms and increase the chance for a full or partial recovery.

When should I call my doctor?
If you or a loved one has the classic triad of symptoms, call your doctor about getting a CT scan and evaluation to test for NPH.

Terms to know

Acquired hydrocephalus — This refers to hydrocephalus that occurs later in life.

Central nervous system (CNS) — This is made up of the brain and spinal cord.

Cerebrospinal fluid (CSF) — This is the water-like fluid that circulates around the brain and spinal cord. It serves to cushion and protect the CNS, as well as to balance nutrients and remove waste products.

Communicating hydrocephalus — This is a type of hydrocephalus that results from an overproduction of cerebrospinal fluid or an underabsorption of fluid into the bloodstream.

Congenital hydrocephalus — This is a type of hydrocephalus that is present at birth.

Hydrocephalus — Hydrocephalus is an abnormal accumulation of water-like fluid in the head. From the Greek "hydro," meaning "water," and "cephalus," meaning "head."

Non-communicating hydrocephalus — This is a type of hydrocephalus that results from a blockage that interferes with the flow of CSF. It is also referred to as obstructive hydrocephalus.

Obstructive hydrocephalus — This is a type of hydrocephalus that results from a blockage that interferes with the flow of CSF. It is also referred to as non-communicating hydrocephalus.

Shunt — This is an implantable device that drains excess fluid from the brain and spinal cord, and diverts it to another part of the body, such as the abdomen or heart, where it can be absorbed.

Ventricles — These are the spaces within the brain where cerebrospinal fluid is made.

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This information is provided by the Cleveland Clinic and is not intended to replace the medical advice of your doctor or health care provider. Please consult your health care provider for advice about a specific medical condition. For additional health information, please contact the Center for Consumer Health Information at the Cleveland Clinic (216) 444-3771 or toll-free (800) 223-2273 extension 43771. If you prefer, you may visit or This document was last reviewed on: 5/18/2016