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Women's Health: Your Body, Your Hormones, Your Choices --- September 11, 2007
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Holly L. Thacker, M.D., F.A.C.P.
Director
, Women's Health Center
Women's Health and Breast Pavilion
Director
, Women's Health Fellowship Associate
Professor
of Surgery, Cleveland Clinic Lerner
College of Medicine (CCLCM) of
Case Western Reserve University (CWRU) Cleveland Clinic, Cleveland, Ohio
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Cleveland_Clinic_Host: Welcome Dr. Thacker and thank you for joining us today. Let's begin with one of the questions. Speaker_-_Dr__Thacker
: Thank you for having me.
Women’s
Health – Frequently Asked Questions
meekkn: I feel I
need a quality physical. I just feel that something isn't right. What do
you tell the physician? Being thorough is not what I'm getting from my
physician. I want a quality examination with blood testing and answers.
How do I get a thorough exam without being offensive to the
physcian? Speaker_-_Dr__Thacker: It is very
important to feel comfortable with your physician and be able to get a
comprehensive exam and testing that is appropriate for your age and
gender. I start on discussing how to find the right doctor in my recently
published book 'Your Body, Your Hormones, Your Choices- A Cleveland Clinic
Guide' 2007 Cleveland Clinic
Press.
emschick: I have recently had a hysterectomy- now I am having problems and my doctor says it's nothing. Do I need a second opinion? Speaker_-_Dr__Thacker: Absolutely! You
need at least a hormonal evaluation and possibly bone evaluation.
newtonm: If taking the depo shot for birth control/control of menstrual cycle, how long is it safe to take? Speaker_-_Dr__Thacker: After two years of
use of depo-provera for contraception, it is advisable to get a bone
density test to make sure you are not loosing bone.
gollygee: With no
family history of breast cancer, how often should I have a
mammogram? Speaker_-_Dr__Thacker: All women age 40
and older should have a yearly mammogram. It is best to schedule your
mammogram right after your period as the breasts are less tender. Do not
schedule your mammogram right before some big event or travel because up
to 1 in 2 women get called back for extra views of the breast, a so called
'diagnostic mammogram'. For many women, this causes anxiety. I think it
best just to plan that you might have to go back in a week or so for extra
views, rather than to get anxious and fret. Do be sure to always schedule
a YEARLY mammogram. Mammograms save lives through early detection. Do it
for yourself, do it for your family.
WQTTIGER: My sister has been diagnosed with the H-POXY infection in her stomach and a swollen liver,high blood pressure Stage II, back pain, blood in urine, she has had gastromitis, and Hiatal Hernia, and skin cancer which she has had removed from inside mouth, dorsal hand tumor. What could be wrong with her? Speaker_-_Dr__Thacker: I presume you mean
h. pylori infection. I’d recommend evaluation starting first with a
general internist.
jennifer36: I have been diagnosed with a
mitral valve and tricuspid valve insufficiency. To what grade I don't know
until I go back to the cardiologist Sept 20 Do they have to stop your
heart to fix the valves? If I am 36 years old, 350 pounds and an apple
shape with most of my weight on the top and breasts, do you think I would
even be a candidate for the minimal invasive or would I most likely have
to have the chest opened? I would never have known this if my feet and
ankles didn't swell out of nowhere and I had an Echo Cardiogram b/c of it
and I have to wait for the actual results from the doctor. Speaker_-_Dr__Thacker
: There is a live chat
tomorrow with the Heart Center and you might want to ask this question
again then. You really should discuss these concerns with a
cardiologist.
lwthu: Is it normal for premenopausal women to
have a stinky smell? Several tests have been done but revealed no
infection (GC, Chlamydia, Yeast, STD). Have experienced NO discharge. No
amount of perfume is covering it. Is there any solution? Thank you so
much- Will appreciate your input. Speaker_-_Dr__Thacker
: I recommend the use of over the
counter repHresh vaginal gel-it lowers the pH of the vagina which helps
keep odor causing bacteria out of the vagina.
maryb: If a woman has a history of lumpy breasts, which sometimes cause concern after mammograms, is hormone replacement contraindicated if there is no personal or family history of breast cancer? Speaker_-_Dr__Thacker
:
Hormone therapy in NOT contraindicated in women with fibrocystic breast
disease. If women have breast tenderness and/or breast cysts, we may use
much lower doses and sometimes will recommend that hormone therapy be
stopped 1-2 weeks in advance of the yearly mammogram especially if a woman
has very dense breasts. Most women with fibrocystic breasts can use
hormone therapy if needed and in general we use the lowest effective dose.
There are many newer lower dose options that allow a woman and her
physician to individualize therapy.
bonnielass: I am 44, am in great health and
work out 5 days a week. I have had problems with very heavy flow the last
3-4 years. I have done all the preliminary testing (Pap, uterine biopsy,
ultrasound, etc.) and everything looks good. If you take the body's
natural rhythm and function of having a period each month away, will the
body and hormones figure out something is wrong and throw me into
menopause early? Speaker_-_Dr__Thacker
: It
sounds as if your doctor might have recommended taking the pill or
hormonal contraception (HC) in a continuous fashion to prevent menstrual
periods and/or reduce the frequency or length of the periods. In general,
this is a very acceptable option for many women (provided they do not
smoke, have blood clots or other medical conditions that preclude the use
of hormonal contraception). Using treatments like long cycle pills or
actually ANY birth control pill taken continuously (with the placebo/sugar
dummy pills thrown away) is an option to reduce heavy flow and/or lengthen
out periods. The Mirena IUS-inserted into the uterus is another option for
women with heavy flow. Endometrial ablation, where the lining of the
uterus is ablated/permanently remove/reduced is another option as long as
the woman is not planning further pregnancies. In my book, "Women's
Health: Your Body, Your Hormones, Your Choices, A Cleveland Clinic Guide,"
I have a chapter on abnormal bleeding and what to do about it. Taking the
pill will not throw you into an early menopause. The trend is to use HC
for longer durations to reduce or even eliminate menstruation. I
personally take long cycle HC and I'm the one to decide if and when it is
convenient for me ‘to have a period.’ I tell women if you are worried
about not losing blood every month you can always visit the Red Cross to
donate your blood!
Hormone Therapy: One Size
Does Not Fit All
sallybgood: What
is the latest health information on hormone replacement
therapies? Speaker_-_Dr__Thacker: There is
information published almost daily about menopausal hormone therapies. An
excellent resource for unbiased information is the North American
Menopause Society web site www.menopause.org, an organization dedicated to
women's health by educating both health care providers and the lay person
about women's health though a better understanding of the study of
menopause.
b3vfoley: What is the best way to test your hormone level? Speaker_-_Dr__Thacker: It is NOT
salivary levels. We can sometimes get blood hormone levels, but the most
important assay is what is in the body tissues such as the bone and the
vagina. I discuss how we do a menopausal hormone assessment in my book,
'Your Body, Your Hormones, Your Choices-a Cleveland Clinic Guide'. The
book provides a lot of detail concerning this question.
newtonm: What guidelines are generally followed with respect to offering hormone replacement to a woman? Speaker_-_Dr__Thacker: All decisions
about hormone therapy (HT) need to be individualized. The new term is HT
as opposed to HRT (hormone replacement therapy). Most naturally menopausal
women have the option of therapy, and not all women need hormone
replacement as menopause is a normal and natural life event. However,
women with early or premature menopause many times need HT/replacement.
Most women with menopausal symptoms who are recently menopausal are
actually good candidates for hormone therapy (HT), particularly if they
have symptoms that disrupt the quality of their life. Midlife is a great
time to reassess your overall health. If you are considering HT, you need
to undergo an individualized history, physical exam and risk-benefit
assessment with your doctor. Therapy should be highly individualized and
periodically assessed. In my recently published book, ‘Women's Health:
Your Body, Your Hormones, Your Choices, a Cleveland Clinic Guide,’ I go
into detail on how to find a women's health doctor who will listen to you
and offer you an individualized assessment. I discuss in great detail the
pros and cons of various hormone regimens and other non-hormonal
treatments for women. Many women are great candidates for HT, do well and
feel well on HT. Other women breeze through menopause and do not need any
HT but may have bone, vaginal and or bladder issues that need to be
assessed.
newtonm: What are
your thoughts on hormone replacement therapy that uses patches versus the
oral version? Speaker_-_Dr__Thacker: There are pros and
cons with each regimen. In my book I have an entire chapter titled
‘Customizing Hormone Therapy: one size does not fit all.’ The use of
patches and creams may be associated with a lower risk of clot and are
many times preferred by women seeking 'bio-identical hormone therapy' as
transdermal-via skin, as well as via vagina mimics more closely how the
ovary delivers estrogen to the body. Conversely, oral regimens may be
better for some women with skin or hair problems as oral HT can reduce
elevated testosterone levels that can cause hair thinning, acne and a
deepening of the voice. If taking oral HT - taking it with food lessens
the effect on the liver. Some vaginal rings have estrogen that affects
only the vagina and bladder - like Estring and some estrogen rings have
higher doses that affect more than just the vagina.
crusher: Please discuss the pros/cons and myths of HRT? Do you recommend bio-identical hormones over other types? Speaker_-_Dr__Thacker: Yes - the heart of
my book is dedicated to these very important questions. Many people
over-estimate the risk of hormone therapy. Hormone therapy needs to be
individualized. Many women are hood-winked by compounding pharmacists that
tell them that compounded hormone therapy is risk free and safer than
prescription or conventional hormone therapy. I prescribe bio-identical
hormones, bio-similar hormones as well as bio-antagonistic hormone therapy
depending on the woman's individual medical history and
concerns.
happyme: Is it
possible that your cholesterol and blood pressure might rise when you stop
taking hormones? Speaker_-_Dr__Thacker: Yes, it is
possible. Some women will have an increase in the LDL-cholesterol - the so
called 'bad' cholesterol - and a decrease in the so called 'good'
cholesterol - HDL-cholesterol - when they stop estrogen. Some women have
very slight decreases in mean blood pressure on HT, so when they go off
they may notice rises. The good news is that healthy diet and exercise and
weight management will control most of these minor changes. Using HT
(hormone therapy) to treat cholesterol or blood pressure is not
recommended.
calico288: Hello
Dr. Thacker, I am a 61-year old woman on hormone replacement (.625 mg.
estrogen and 100 mg. progesterone daily) for 5 1/2 years and am getting
spotting or bleeding much of the time now, usually just enough to be a
real nuisance. I don't want to go off HRT because both my parents, my
grandmother and my uncle had dementia for years before they died and I am
getting osteoporosis. I am not at risk for breast cancer and am quite
physically active and eat well. My doctor does not support me being on HRT
and just says ‘go off it’ when I mention the spotting, but I have read
much research supporting estrogen for preventing dementia. Can you suggest
a way that I could stop the bleeding without going off the hormones?. Any
help appreciated, and thank you. Speaker_-_Dr__Thacker: If you take both
estrogen and progesterone daily after 6 months there should not be
bleeding or spotting. You need to have an evaluation of the
endometrium/lining of the uterus with an outpatient endometrial sampling
and/or a transvaginal ultrasound. Likely the doses of the hormone therapy
(HT) need to be adjusted. We don’t use HT solely to prevent dementia. In
older women HT does not treat or prevent dementia though in women taking
HT for menopausal symptoms, the observational research suggests a
reduction in the risk of dementia. Controlled blood pressure, cholesterol,
weight and risks for heart disease also reduce the risk for stroke and
memory loss. I’d suggest you see a North American Menopause Society (NAMS)
credentialed menopause specialist for evaluation.
b3vfoley: Is estrogen, progestrogen and testostrogen closely linked to the autoimmune system? Speaker_-_Dr__Thacker: Yes, these hormones
have effects on the immune system and the entire body. In general, women
have a more 'active immune system' hence they recover from infections like
viruses faster than men. However, they have a higher rate of autoimmune
conditions such as Hashimoto's thyroid (female to male ratio is 50 to
1)
jbf: What is progesterone cream used for? Speaker_-_Dr__Thacker: It has been used
for women with PMS and/or perimenopausal symptoms.
kathyk: What do
you think about progesterone cream? Speaker_-_Dr__Thacker: Progesterone creams
obtained over-the-counter may or may not contain progesterone. Many only
have diosogen - the precursor to progesterone - which only plants, NOT
humans, can convert to progesterone.
kathyk: Do you
need a doctor's prescription to get progesterone cream and does it have
any adverse effects? Speaker_-_Dr__Thacker: Some progesterone
creams have been found to reach blood levels like with prescription oral
or vaginal progesterone, so there can be definite hormonal effects. Even
though they are purchased over-the-counter, patients who use them need to
be monitored by a physician. Conversely, blood levels may not be high
enough so progesterone cream can NOT be relied upon to protect the uterus
in women who need progesterone therapy.
Post-Menopause
jacksonp: After menopause and the use of hormone replacement therapy, is it necessary for a woman to see a gynecologist or is it no longer necessary? Speaker_-_Dr__Thacker: All women should
continue to have yearly breast/genital and pelvic exams.
Endometriosis and
Fibroids
maddiegirl: Dr. Thacker - I had endometriosis and was treated about 20 yrs ago with Danazol. I had two IVF procedures and was hyperstimulated with the 2nd one. No pregnancies - we ended up adopting. Can endometriosis return later? I have abdominal discomfort and tenderness but I have always considered that to be normal. Will the endometriosis just disappear with menopause? Speaker_-_Dr__Thacker: Usually,
endometriosis, like fibroids regress during menopause. Based on your
symptoms, you should see a physician for evaluation as opposed to just
attributing them to endometriosis.
goldie: What are
fibroids? How do you get them? Speaker_-_Dr__Thacker: Fibroids are benign
muscle growths of the uterus and up to 1 in 2 women have them. They may or
may not cause problems.
toonces: If it is
discovered you have 8 fibroids - would you suggest a complete
hysterectomy? Speaker_-_Dr__Thacker: No, not necessarily. It
depends on the symptoms, size of the fibroids and the bleeding pattern.
There are many non-hysterectomy alternatives that I detail in my
book.
The Book ‘Women’s Health:
A Cleveland Clinic Guide’
Cleveland_Clinic_Host: Dr. Thacker, can you tell us a little bit more about your book? What topics do you cover? Is it a book that someone in her 40's would find useful or what about someone that is in her 60's? Speaker_-_Dr__Thacker: My book covers a
myriad of interesting Women's Health topics from menstrual disorders to
migraines to menopause as well as bone health, sexual health. There are
also important comments about nutrition, vitamin supplements and exercise.
I think that women ages 30-80+ will find the book interesting and
helpful.
Hot Flashes, Mood Swings
and More
maddiegirl: Actually, I just finished reading your book and enjoyed the wealth of information. I am 50 yrs. old, probably Perimenopause although my symptoms are mild. But, when I sleepmy legs and sometimes whole body will sweat despite a cool room, fan, cotton sheets and light PJ's. I'm not sure I consider this a hot-flash or the beginning of one. I have tried everything but sleeping with socks.. Does that really work? Or, am I approaching a time to start inquiring about Hormone Therapy? Speaker_-_Dr__Thacker: It sounds like you
are having hot flashes and night sweats. Yes, it would now be a good time
to discuss options of hormone therapy and or other treatments.
jbf: What are some of the most successful ways to deal with hot flashes and mood swings? Speaker_-_Dr__Thacker: In the book, there
is a chapter on 'Maintaining Mood at Midlife,' that reviews the various
mood stabilizing treatments and talks about which comes first, menopause
or depression? Estrogen treats hot flashes and is a mild mood elevator,
but is not a standard treatment for depression. Whereas antidepressants
like Effexor/venlafazine in low doses treat menopausal hot flashes, in
higher doses they don't help hot flashes too much. However, they do treat
depression and anxiety. Sometimes vitamins, nutritional supplements,
exercise, omega 3 fatty acids, and lifestyle changes are enough to treat
minor hot flashes and mood changes. Sometimes hormone therapy is needed.
Other times, antidepressant therapy is needed. Sometimes both treatments
are needed! In my book, I detail how a doctor and an individual woman can
go about dealing with vexing mood symptoms and perimenopausal symptoms
which can collide at the same time! In the future, we are expecting the
first FDA approved non-hormonal medication, Prestiz/Desvenlafaxine to
treat hot flashes. Currently, only hormonal products are FDA approved to
treat menopausal hot flashes.
gettingold: Are
any natural supplements available for hot flashes and vaginal
dryness? Speaker_-_Dr__Thacker: I've mentioned the
use of either vitamin E oil or olive oil for the vagina. Black cohosh, in
the form of remifemin, has been used to treat hot flashes/night sweats for
up to 6 months. Some women who eat soy foods convert soy protein into
equol, a weak estrogen, and this may blunt their flashes. However, we do
NOT recommend taking high doses of soy pills/powders, only soy in the form
of whole foods, as soy pill supplements have been linked to uterine
stimulation.
health1234:
Menopausal vaginal dryness has been a significant problem for over two
years; replense and other aids are no longer working. I have not used the
E-ring replacement for fear of the estrogen risk. This continues to cause
problems that my research has not found other answers to. I have not had
breast or other cancers, but do have chronic low neutrophile counts. Are
there any suggestions you may have? Thank you. Speaker_-_Dr__Thacker: In general, there
is NO reason why a woman can not use Estring as it ONLY affects the
vagina-it does NOT increase estrogen levels in the blood stream. It is
unfortunate that you are suffering with excess fear related to
misinformation about estrogen. In the book, I discuss how we even use the
Estring vaginal ring in breast cancer survivors. Vitamin E oil and olive
oil are the only 2 oils that are fine to use as a 'natural'
lubricant/moisturizer.
carlie: What
causes a woman, as they age, to grow hair in places they never had hair
before (i.e. chin and upper lip)? Does taking and/or stopping different
forms of birth control cause this? Speaker_-_Dr__Thacker: When women go into
menopause, their estrogen levels begin to drop, but the testosterone
levels may not. Therefore, they may develop chin whiskers, deepening of
the voice and male-patterned hair thinning. In younger women, birth
control pills actually reduce testosterone levels which may improve hair
and skin problems.
Vitamin
D
survivor: What is
your response on getting enough Vitamin D, especially in areas of the
country with limited sunshine? Speaker_-_Dr__Thacker: Most people need to
take a Vitamin D supplement. Recent evidence has suggested that adequate
levels of Vitamin D intake can reduce cancer incidence by 70% and increase
longevity. Even areas in the country with more sunshine than Cleveland, OH
up to 50% or more of the general population are Vitamin D insufficient. I
recommend 1,000 IU of Vitamin D3 (cholecalciferol) daily. It is very easy
for your doctor to check your Vitamin D level with a 25-OH Vitamin D
level. Again.
Ovarian
Cancer
crusher: Isn't there a screening test for ovarian cancer that can be done with the yearly exam similar to a man's PSA test for prostate cancer? If there is, then why aren't doctors performing it routinely? Is it an insurance issue? This would be a great tool as many ovarian cancers are not detected early enough! Speaker_-_Dr__Thacker: Actually, the
answer is NO. It is too bad that we do not yet have a simple blood test to
screen for ovarian cancer. Cleveland Clinic researchers are working on
this. Emails telling you to get your CA-125 test unfortunately are just a
hoax. In normal women, this is NOT a screen for ovarian cancer. Many
doctors will go ahead and order the test if you ask them rather than
explain that a normal test does not exclude ovarian cancer AND an abnormal
test does not diagnosis ovarian cancer. An abnormal test result could
actually lead to having your normal ovaries surgically removed.
Dianne: I am 60
y/o recently dxd with dermoid cyst on the left ovary. CA-120 marker is not
elevated. A total hysterectomy has been recommended. What are the
advantages/disadvantages over just having a lap and having the cyst
removed? If one is post-menopausal, is there any estrogen secretion going
on in the ovaries? Are there studies in post-menopausal women regarding
removal of ovaries/estrogen and dementia? Speaker_-_Dr__Thacker: In general, we like
to preserve the ovaries up to age 65 yrs. because there continues to be
hormone secretion. However, if there is cancer it is best to have a
complete hysterectomy. It is important to find a surgeon that you feel
comfortable with and will offer you all of your choices. In young women,
particularly under age 35, that have their ovaries removed without benefit
of estrogen therapy, there is a higher risk of both heart disease and
osteoporosis.
Osteoporosis
PeppermintPatty: I am 60 years old. Do medications and calcium supplements help prevent progression to osteoporosis? Speaker_-_Dr__Thacker: Yes, but don't
forget the 1,000 international units of Vitamin D3 daily.
sallybgood: Is
joint pain tied to menopause? Speaker_-_Dr__Thacker: Joint pain is NOT a
classic menopausal symptom, although there are estrogen receptors on the
cartilage and some postmenopausal women do report less stiffness on HT. I
recommend good nutrition, calcium, vitamin D (800 to 1,000 international
units daily) and a sound exercise program after consulting with your
doctor. Weight loss, physical therapy and selected use of medicines and
even joint injections may be needed for some women. Glucosamine is a
supplement that has been shown to decrease knee osteoarthritis symptoms in
some postmenopausal women.
PeppermintPatty: I
have osteopenia. Is the progression to osteoporosis
inevitable? Speaker_-_Dr__Thacker: Not
necessarily.
Diet and
Exercise
crusher: Ever since I've slipped into the menopausal abyss, I've packed on 10-15 lbs that will not go away despite diet and exercise. Any suggestions? Once I get to the other side of menopause will the added weight come off? If I'm not having serious menopause symptoms I wouldn't want to start HT just for weight control. Speaker_-_Dr__Thacker: Unfortunately, your
metabolism takes a nose dive during menopause. You actually have to eat
less and exercise more just to prevent weight gain! However, women on
hormone therapy tend to be leaner than women not on hormone therapy BUT
this is not a sole reason to take hormone therapy. I would recommend daily
exercise for one hour a day with weight lifting exercises. You also may
want to have your thyroid function tested.
newtonm: I've recently heard that weight that is gained around the waist is very ‘active’ and produces estrogen. Although I am in the process of losing weight, how does it factor into the doctor determining the correct amount of hormones one should take? Speaker_-_Dr__Thacker: Too much body fat
anywhere can by harmful. The weight around the belly is linked to a higher
rate of diabetes, cancer and heart disease, while weight around the hips
and thighs is less harmful. Too much body fat can increase hormone levels,
although not always. Women who are overweight have a higher risk of breast
and uterine cancer.
bjones: What are
the benefits of taking the omega 3 fatty acids and how much we need to
take per day? Speaker_-_Dr__Thacker: Omega 3 fatty acids are
important for brain, breast, and heart health. It is important to ingest
at least 2 servings weekly (not daily).
Cleveland_Clinic_Host: I'm sorry to say that our time with Dr. Thacker is over. Dr. Thacker, thank you again for taking the time to answer our questions today. Speaker_-_Dr__Thacker: Thank you ladies,
this has been an enjoyable chat. For more information, don't forget to
look for my book!
Cleveland_Clinic_Host: If you would
like more information regarding Women's Health, please visit the Cleveland
Clinic Women’s Health web site at
http://www.clevelandclinic.org/womenshealth. For general health
information you may also wish to visit http://www.clevelandclinic.org/health/. |