Research Commercialization Projects

GCIC sponsored commercialization projects are bringing Ohio-developed cardiovascular technologies out of the laboratory and into the marketplace.

Bioprosthetic Valves for Minimally Invasive and Percutaneous Delivery

This technology is a specially designed tissue heart valve that allows for stable placement that is adaptive to cardiac anatomy.

CD36 Inhibitor Targeting

The goal of this study is to treat atherosclerosis through the inhibition of the CD36 protein.

Corin Assay Diagnostics

This technology is based upon the discovery of corin, a cardiac protein, which can be used as an indicator for chronic heart failure.

Electrostatic Spinning of Biodegradable Nanofibers

This process provides a novel production method for vascular stents and grafts via electrospinning, a highly precise and adaptable method for creating polymer-based devices.

GP Ib a Inhibitors

This project aims to develop novel pharmaceuticals to target early events in vascular injury, such as heart attack, restenosis and vasculitis.

Minimally Invasive Fiberoptic Cardioscopy

The goal of this project is to develop and commercialize fiberoptic instrumentation that allows minimally invasive, direct visualization of cardiac structures.

MiniMixedFlow Rotary Blood Pump

This minimally invasive heart pump technology is a scalable platform technology that includes a miniature version deliverable via catheter, suitable for pediatric needs, and larger models for adult patients.

Mitral Annular Remodeling

This novel procedure can treat mitral valve regurgitation through tissue remodeling by the injection of a synthetic biomaterial.

Myo Annuloplasty Ring

This technology is a novel, self supported annuloplasty ring for the treatment of heart valve regurgitation that can be deployed minimally invasively or perucutaneuously.

TNF-a Receptor-II Inhibitors

This Cleveland Clinic study aims to develop novel therapeutics for inflammatory diseases, such as atherosclerosis, through inhibition of molecule TNF-a Receptor-II.

Transvascular Neurostimulation System

A joint effort between vascular and neuroscience researchers has led to the development of neuromodulation devices that allow regulation of cardiovascular function.