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Sunita Radhakrishnan1, Yan Li 2,3,4, David Huang3,4, Volker Westphal2, Raj Shekhar4, Andrew M. Rollins1, Joseph A. Izatt2
Departments of Medicine1 and Biomedical Engineering 2, Case Western Reserve University, Cleveland, Ohio; Cole Eye Institute3 and Lerner Research Institute4, Cleveland Clinic Foundation, Cleveland, Ohio.
Purpose: To compare optical coherence tomographic (OCT) imaging of LASIK flaps using 0.8 micron and 1.3 micron wavelengths of light.
Methods: Nineteen subjects who had undergone LASIK surgery were enrolled in the study. Corneal OCT scans were taken with an arc-scanning prototype operating at a wavelength of 0.8 micron and/or a high-speed OCT prototype at a wavelength of 1.3 micron. Three scans of the central cornea were taken preoperatively and 1 day and 1 week postoperatively. Images obtained with each system were analyzed for reflectivity characteristics of the LASIK flap.
Results: LASIK flaps imaged with the real-time 1.3 micron OCT system showed increased internal reflectivity as well as higher interface reflectivity when compared with those imaged with the 0.8 micron system. The flap could be visualized in 100% of cases at first postoperative day with the 1.3-micron system, but only in 15-20% with the 0.8-micron system. The 1.3-micron wavelength also allows the use of higher power, which enables image acquisition with sufficient speed (0.12 sec) to eliminate most motion artifacts.
Conclusion: 1.3 microns is the preferred wavelength for OCT imaging of the cornea.
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