Tiffany Kaul
A Radiological Investigation: Support for a Spinal Stenosis and CSF Ventriculomegaly Relationship

SchoolSolon High School


ProgramScience


MentorStephen Dombrowski, PhD


DepartmentNeurosurgery


Research
A Radiological Investigation: Support for a Spinal Stenosis and CSF Ventriculomegaly Relationship
Hypothesis
Patients diagnosed with spinal stenosis will have a higher incidence of ventriculomegaly, and the degree of the stenosis will be directly correlated to the severity of the ventriculomegaly.
Methodology
This study looked at 668 patients who have had MRI of both head and spine at Cleveland Clinic for medical or surgical evaluation from 2005 to 2008. A total of 216 patients met the inclusion criteria; 62 had complete MRI tracings of head and spine and had completed chart reviews. MR images were collected to measure degree of ventriculomegaly and degree of spinal stenosis. Area contours of brain and CSF spaces were manually traced from axial images at the level of the Foramen of Monroe, and contours of the spinal canal and spinal cord of the cervical and lumbar regions were traced from mid-sagittal images. Linear measurements were taken from head at the level of the Foramen of Monroe and from the spine, orthogonal to the spinal cord between each disk.
Outcomes
We found an indication that a relationship exists between cranial-spinal CSF communication (i.e. spinal stenosis) and ventriculomegaly. The results indicate that the hypothesis is true but there are not enough traced MRIs of those with ventriculomegaly to verify validity.

Interpretations

Spine by Natalie Salvaggio