Steven Zhou
Effects of Lung Mechanics on Oxygen Delivery with Nasal Cannulae

SchoolHudson High School

ProgramRespiratory Therapy

MentorRob Chatburn

DepartmentRespiratory Institute

Effects of Lung Mechanics on Oxygen Delivery with Nasal Cannulae
We hypothesize that simulated FiO2 would be affected by lung condition. Specifically, we tested these hypotheses: 1. FiO2 is lower in chronic obstructive pulmonary disease (COPD) than normal lungs for low flow cannula. 2. FiO2 is the same for COPD and normal lungs for high flow cannula.
A lung simulator (ASL 5000, Ingmar Medical, Inc.) was used to test high and low flow nasal cannulae to determine the difference in the FiO2 levels between simulated patients with normal lung function and those with COPD. As such, respiratory flows and lung mechanic parameters were set to emulate a normal adult lung and one with COPD. The effectiveness of these two respiratory modalities was evaluated by measuring the FiO2.
The data fully support hypothesis 1. There was a statistically significant and clinically important difference between the fraction of inspired air between patients simulated using the normal and COPD lung models. Hypothesis 2 was supported for the two highest flows in our study (40 and 60 L/min). With lower flows, there is still a significant difference in oxygen delivery.


Untitled by Erika Klemperer