Finding Balance through Innovation

MONDAY, NOVEMBER 10, 2008

12:00 - 7:00 P.M.

Registration

12:00 P.M.

Exhibits Open 2nd and 3rd Floors: Light Refreshments

2:00 - 2:10 P.M.

Delos Cosgrove, MD
Chief Executive Officer and President
Cleveland Clinic

Welcome

Tribute to Andrew Novick, MD
Founding Chairman, Glickman Urological and Kidney Institute
Associate Dean for Faculty Affairs, Cleveland Clinic

2:10 - 2:20 P.M.

Eric Klein, MD
Vice Chairman, Glickman Urological and Kidney Institute
Cleveland Clinic

Summit Preview

2:20 - 3:45 P.M.

After the Smoke Clears: Analyzing the 2008 Elections and Their Impact on Medical Innovation
Charlie Cook
Publisher, The Cook Political Report, Panel Chair

• Glen Bolger
  Partner, Public Opinion Strategies
• Chris Jennings
  President, Jennings Policy Strategies
• Tim Ring
  Chief Executive Office, CR Bard

3:45 - 4:45 P.M.

Forecasting the 111th Congress: Will healthcare Innovation and Access Be Capitol Hill Priorities?
Thalia Assuras
Anchor, CBS Saturday Evening News, Moderator
Honorable Ron Wyden
United States Senator, D-Oregon

4:45 - 5:30 P.M.

The Innovation Opportunity
Thalia Assuras
Anchor, CBS Saturday Evening News, Moderator
Karen Licitra
Company Group Chairman, Ethicon Endo-Surgery, Johnson & Johnson

6:30 - 10:00 P.M.

Opening Reception, Dinner and Entertainment
Rock and Roll Hall of Fame and Museum

TUESDAY, NOVEMBER 11, 2008

6:30 - 9:00 A.M.

Registration

6:30 - 7:30 A.M.

Continental Breakfast

7:00 - 2:00 A.M.

Exhibits Open 2nd and 3rd Floors

6:30 - 7:30 A.M.

Continental Breakfast

7:30 A.M.

Chris Coburn
Executive Director,
Cleveland Clinic Innovations

Welcome

7:30 - 8:30 A.M.

Live Surgery: Renal Surgery Innovations
Steven Campbell, MD, PhD,
Staff, Urologic Oncology, Glickman Urological and Kidney Institute, Cleveland Clinic, Moderator

• Laparoscopic Partial Nephrectomy,
  Surgeon: Inderbir Gill, MD,
  Cleveland Clinic
• Single-Port Prostatectomy,
  Surgeon: Mihir Desai, MD,
  Cleveland Clinic
• Single Port Renal Cryoablation,
  Surgeon: Jihad Kaouk, MD,
  Cleveland Clinic

8:30 - 9:15 A.M.

Richard Roth,
CNN Correspondent, Moderator of Morning Sessions
Moderator of Morning Sessions

Extending Clinical Excellence
Ronald Riner, MD,
President, The Riner Group, Panel Chair

• Eric Klein, MD,
  Acting Chairman, Glickman Urological & Kidney Institute Director,
  Center for Urologic Oncology, Cleveland Clinic
• Bruce Lytle, MD,
  Chairman, Heart and Vascular Institute, Cleveland Clinic
• Michael Wiemann, MD,
  President, Providence Hospital

9:15 - 10:00 A.M.

Minimally Invasive and Focal Therapies
J. Stephen Jones, MD,
Chairman, Department of Regional Urology, Glickman Urological and Kidney Institute, Cleveland Clinic, Panel Chair

• John Kurhanewicz, PhD,
  Professor, Radiology and Biomedical Imaging, Pharmaceutical Chemistry & Urology, UCSF, Mission Bay
• Kevin Quilty,
  Senior Vice President, Endocare
• John Rewcastle, PhD,
  International Medical Director, EDAP TMS
• Kobi Vortman, MD,
  Chief Executive Officer, InSightec

10:00 - 10:20 A.M.

Break

10:25 - 11:05 A.M.

NOTES and Single-Port Laparoscopy

• Inderbir Gill, MD,
  Department Chair, Urology, Glickman Urological and Kidney Institute, Cleveland Clinic, Panel Chair
• Frank Bonadio,
  Chief Executive Officer, Advanced Surgical Concepts
• Mihir Desai, MD,
  Director, Center for Endourology and Stone Disease, Department of Urology, Glickman Urological and Kidney Institute, Cleveland Clinic
• Anthony Kalloo, MD,
  Chief, Division of Gastroenterology and Hepatology, Johns Hopkins Hospital
• Karen Licitra,
  Ethicon Endo-Surgery, Johnson & Johnson
• Michael Tarnoff, MD,
  Chief Medical Officer and Vice President Medical Affairs, Covidien

11:05 A.M. - 11:45 P.M.

Advances in Laparoscopic and Robotic Surgery
Jihad Kaouk, MD,
Director, Center for Robotic Surgery, Department of Urology, Glickman Urological and Kidney Institute, Cleveland Clinic, Panel Chair

• Eric Halvorson,
  Chief Marketing Officer, Olympus America
• Woojin Lee, PhD,
  President, CambridgeEndo
• Fredric Moll, MD,
  Chief Executive Officer, Hansen Medical
• Gregory Piskun, MD,
  Chief Executive Officer, Pnavel Systems
• Kerry Pope,
  Chief Executive Officer, Novare Surgical Systems
• Clement Vidal,
  Chief Executive Officer, EndoControl

11:45 - 12:25 P.M.

Female Pelvic Medicine and Reconstructive Surgery
Marie Paraiso, MD,
Director, Center for Urogynecology and Reconstructive Pelvic Surgery, Co-Director, Program for Female Pelvic Medicine and Reconstructive Surgery, OB/GYN and Women's Heath Institute, Cleveland Clinic, Panel Chair

• Anthony Atala, MD,
  Chair, Dept. of Urology, and Director, Institute for Regenerative Med.,
  Wake Forest University School of Medicine
• Ross Longhini,
  Chief Operating Officer, AMS
• Raymond Rackley, MD,
  Professor of Surgery, Center for Female Pelvic Medicine & Reconstructive Surgery, Glickman Urological and Kidney Institute
• David Robinson, MD,
  Medical Director, Ethicon Women's Health and Urology

12:30 - 1:45 P.M.

Lunch: Founders Ballroom

Shaping the Future: How Innovation, Governments and Business Can Drive Early Health
John Dineen,
Chief Executive Officer, GE Healthcare

• Maria Bartiromo,
  CNBC, Moderator
• Bruce German, PhD,
  Senior Scientific Advisor, Nestle Research Center
• Nicolaus Henke
  Director, McKinsey Global Healthcare, UK

1:55 - 3:10 P.M.

Venture Investing from the Inside Out: An Issues-Oriented, Contemporary Case Study
Harry Rein,
General Partner, Foundation Medical Partners, Panel Chair

• Mike Connolly,
  Chief Executive Officer, Mirabilis
• Martin Emerson,
  Chief Executive Officer, Galil Medical
• Richard Emmitt,
  General Partner, Vertical Group
• Jan Garfinkle,
  Managing Director, Arboretum Ventures
• Michael Greeley,
  General Partner, Flybridge Capital Partners
• Peter Klemm, PhD,
  Chief Executive Officer, Predictive Biosciences

3:10 - 4:00 P.M.

Building an Innovation Culture in Venture Backed
and Fortune 100 healthcare Companies
Michael Roizen, MD,
Chief Wellness Officer, Cleveland Clinic, Moderator

• Larry Keeley,
  President, Doblin
• Craig Wynett,
  General Manager, P&G

4:00 - 6:00 P.M.

Break / Networking Opportunities

6:00 - 7:00 P.M.

Welcome Reception

7:00 P.M.

Dinner: Founders Ballroom

In An Increasingly Uncertain World
Robert Rubin
Director and Senior Counselor, Citigroup

WEDNESDAY, NOVEMBER 12, 2008

6:30 - 9:00 A.M.

Registration

6:30 - 7:30 A.M.

Continental Breakfast

7:00 - 2:00 A.M.

Exhibits Open 2nd and 3rd Floors

7:30 - 8:30 A.M.

Live Surgery: Pelvic Floor Innovations
Sandip Vasavada, MD,
Director, Center for Female Pelvic Medicine & Reconstructive Surgery, Department of Urology, Glickman Urological and Kidney Institute,
Cleveland Clinic
Moderator
Matthew Barber, MD,
Vice Chair, Clinical Research in Obstetrics and Gynecology, OB/GYN and Women's Health Institute, Cleveland Clinic
Moderator

• Robotic Surgery for Vaginal Prolapse,
  Surgeon: Marie Paraiso, MD,
  Cleveland Clinic
• Single Port Technique for Vaginal Prolapse,
  Surgeon: Raymond Rackley, MD,
  Cleveland Clinic
• Hysteroscopic Female Sterilization,
  Surgeon: Jonathan Emery, MD,
  Cleveland Clinic
• Cystoscopic Injection of Botox® for Overactive Bladder,
  Surgeon: Courtenay Moore, MD,
  Cleveland Clinic

8:30 - 9:40 A.M.

From Possible to Practical:
Redrawing the Healthcare Landscape Through IT
Martin Harris, MD,
Chief Information Officer, Cleveland Clinic, Panel Chair

• John Kelly, PhD,
  Senior Vice President and Director of Research, IBM
• Dana Mead,
  Partner, Kleiner Perkins Caufield and Byers
• Peter Neupert,
  Corporate Vice President Health Solutions Group, Microsoft
• Steve Oesterle, MD,
  Senior Vice President for Medicine and Technology, Medtronic
• Alfred Spector,
  Vice President of Research and Special Initiatives, Google

9:40 - 10:00 A.M.

Break

10:05 - 10:45 A.M.

Rising Economies and the Opportunities/Threats They Create for U.S. Med Tech Companies
David Strand,
Chief Operating Officer, Cleveland Clinic, Panel Chair

• Manar Al-Moneef, MD,
  Director General, SAGIA Health & Life Science Sector, Saudi Arabia

• Tom Kelly, PhD,
  Director of Lifesciences, Enterprise Ireland

10:45 A.M. - 11:45 P.M.

"Top 10" Medical Innovations for 2009
Michael Roizen, MD,
Chief Wellness Officer, Cleveland Clinic, Moderator

11:45 A.M. - 12:45 P.M.

Female Sexual Dysfunction
Holly Thacker, MD,
Director, Center for Specialized Women's Health, OB/GYN and Woman's Health Institute, Cleveland Clinic, Panel Chair

• Andre Guay, MD,
  Director, Center for Sexual Function / Endocrinology, Lahey Clinic
• Lisa Martinez, RN,
  Executive Director, Women's Sexual Health Foundation
• Joan Meyer, PhD,
  Manager, Women's Health, P&G Pharmaceuticals
• Wulf Utian, MD, PhD,
  Executive Director, North American Menopause Society, Consultant Staff, OB/GYN and Women's Health Institute, Cleveland Clinic

12:45 - 2:00 P.M.

Lunch: Founders Ballroom

Medical Innovation in Time of Economic Stress
Jim Tobin
Chief Executive Officer, Boston Scientific

2:00 - 2:30 P.M.

Reflections on the Direction of Healthcare Innovation During the Next Four Years
Honorable Tommy Thompson
Former Governor of Wisconsin and U.S. DHHS Secretary

2:30 - 2:45 P.M.

Wrap Up
Joseph Hahn, MD
Chief of Staff, Cleveland Clinic

MONDAY, OCTOBER 1, 2007

12:00 - 7:00 P.M.

Registration

12:00 P.M.

Exhibits Open - Light Refreshments
2nd and 3rd Floors

2:00 - 2:10 P.M.

Delos Cosgrove, MD
CEO & President , Cleveland Clinic

Welcome

2:10 - 3:40 P.M.

State of Cardiovascular Medicine
Larry King,
Host of CNN's Larry King Live and Founder of The Larry King Cardiac Foundation, Moderator

• Steve Nissen, MD,
  Chairman, Cardiovascular Medicine, Cleveland Clinic, Panel Leader
• Bruce Lytle, MD,
  Chairman, CardioThoracic Surgery, Cleveland Clinic
• Michael Mussallem,
  Chairman-Elect, AdvaMed: CEO, Edwards Lifesciences
• Elizabeth Nabel, MD,
  Director, NHLBI/NIH
• Tony Zook,
  U.S. President & CEO, AstraZeneca

3:45 - 3:55 P.M.

Special Announcement
Ted Strickland, Governor of Ohio

3:55 - 5:15 P.M.

The Press and the Politics of healthcare Reform
Michael McCurry, Partner, Public Strategies Washington, Moderator

• Tim Johnson, MD,
  Medical Editor, ABC News
• Joanne Silberner,
  Health Policy Correspondent, National Public Radio

5:15 - 6:15 P.M.

The Impact of Innovation: Industry Leaders Discuss healthcare's Future
Tim Johnson, MD, Medical Editor, ABC News, Moderator

• Bill Hawkins,
  CEO, Medtronic
• Steve Hemsley,
  CEO, UnitedHealth Group

6:30 - 10:00 P.M.

Opening Reception and Dinner
Cleveland Orchestra
Franz Welser-Möst, conductor
Mozart Symphony No. 28
Tchaikovsky Symphony No. 6
Severance Hall

MONDAY, NOVEMBER 6, 2006

1:00 - 8:00 P.M.

Registration

2:00 P.M.

Exhibits Open - Light Refreshments
2nd and 3rd Floors

4:00 - 4:05 P.M.

Welcome Delos Cosgrove, M.D.
CEO & President, Cleveland Clinic

4:05 - 4:15 P.M.

Cleveland Clinic Neurological Institute Introduction

Michael Modic, MD
Interim Chairman, Neurological Institute
Chairman, Division of Radiology, Cleveland Clinic

4:15 - 5:20 P.M.

Future Technology

• Ray Kurzweil, Futurist and Inventor
• Allen Roses, M.D., Senior Vice President, Genetics Research, GlaxoSmithKline

5:20 - 6:00 P.M.

Innovation, Reimbursement and New Technology in Healthcare
Discussion Moderated by Thomas Stewart
Editor, Harvard Business Review

• Ron Williams, CEO, Aetna

6:00 - 6:30 P.M.

Innovation, Technology, Patient Care and Reimbursement: "Presidents' Perspective"
Moderated by: Richard Ellenbogen, MD, FACS,
President, Congress of Neurological Surgeons

• Joshua Prager, MD, President, North American Neuromodulation Society
• Elliot Krames, MD, President, International Neuromodulation Society

6:45 - 10:00 P.M.

Opening Reception and Dinner
Prelude Concert by Members of the Cleveland Orchestra
Severance Hall
Transportation Provided

TUESDAY, NOVEMBER 7, 2006

6:30 A.M - 2:00 P.M.

Registration

6:30 - 7:30 A.M.

Continental Breakfast

7:00 A.M. - 7:00 P.M.

Exhibits Open
2nd and 3rd Floors

7:30 A.M.

Welcome
Christopher Coburn
Executive Director, CCF Innovations, Cleveland Clinic

7:30 - 9:00 A.M.

Live Surgeries: Neuromodulation
Moderated by: Ali Rezai, M.D., Chairman, Center for Neurological Restoration; Director, Brain Neuromodulation Center, Cleveland Clinic

9:00 - 9:45 A.M.

Managing Costs: Next Steps from Washington
Introduction by Robert Bazell, NBC News' Chief Health and Science Correspondent

• Senator David Durenberger (R-Minn), Retired

9:45 - 10:30 A.M.

Managing Costs: Private Sector Trends
Introduction by Robert Bazell, NBC News' Chief Health and Science Correspondent

• Larry Glasscock, CEO, Wellpoint

10:30 - 10:45 A.M.

Break

10:45 A.M. - 12:15 P.M.

Neuromodulation: Breakthrough Therapy for Refractory
Disease
Moderated by: Ali Rezai, M.D., Chairman, Center for Neurological Restoration; Director, Brain Neuromodulation Center, Cleveland Clinic

• Chris Chavez, CEO, ANS, St. Jude Medical
• Jeff Greiner, Co-CEO, Advanced Bionics
• Rick Kuntz, M.D., President of Neurological Businesses, Medtronic
• Alan Levy, PhD, CEO, Northstar Neuroscience
• Timothy Surgenor, CEO, Cyberkinetics

12:30 - 2:00 P.M.

Lunch - Founder's Ballroom
How to Fix a Guidant: Realizing the Potential of a Strategic Acquisition
Introduction by Mike O'Boyle, Chief Operating Officer, Cleveland Clinic

• James Tobin, President & CEO, Boston Scientific

2:15 - 3:30 P.M.

"Top 10 Medical Innovations for 2007"
Moderated by Marc Penn, M.D., Ph.D.,
Director, Bakken Heart-Brain Institute, Cleveland Clinic

3:30 - 4:00 P.M.

Break

4:00 - 5:00 P.M.

Neuro-Imaging: Shifting the Foundation of Disease
Recognition and Management
Moderated by Michael Modic, M.D., Interim Chairman, Neurological Institute; Chairman, Division of Radiology, Cleveland Clinic

• Micheal Phillips, M.D., Section Head, Section of Imaging Sciences, Cleveland Clinic
• Eric Bailey, Co-Founder, NeuroLogica
• Arani Bose, M.D., Department of Radiology, NYU Medical Center
• Aaron Berez, M.D., CEO, Chestnut Medical
• Peter Kingma, Vice President of Molecular Imaging, Siemens Medical Solutions

5:00 - 6:00 P.M.

Perspectives from the Frontiers of Science
Moderated by Bruce Trapp, Ph.D., Chairman, Department of Neurosciences, Cleveland Clinic

• Stanley Prusiner, M.D., 1997 Nobel Laureate in Medicine, University of California, San Francisco

6:00 - 7:00 P.M.

Welcome Reception

7:00 P.M.

Dinner - Founder's Ballroom
"Diagnosing the Undetectable Through Technology Convergence"
Jeffrey Immelt
CEO and Chairman of the Board, General Electric
Introduction by Delos M. Cosgrove, M.D.

WEDNESDAY, NOVEMBER 8, 2006

6:30 - 9:00 A.M.

Registration

6:45- 7:45 A.M.

Continental Breakfast

7:00 A.M. - 2:00 P.M.

Exhibits Open
2nd and 3rd Floors

7:45 - 8:45 A.M.

Live Surgeries: Cerebrovascular Aneurysms
Moderated by: Thomas Masaryk, M.D., Head of Neuroradiology, Cleveland Clinic

8:45 - 10:15 A.M.

Neuroscience, Entrepreneurship and Venture Investing
Moderated by Harry Rein, General Partner, Foundation Medical Partners

• John Harris, President & CEO, BioNeuronics
• Andrew Firlik, M.D., Partner, Foundation Medical Partners
• Frank Fischer, CEO, NeuroPace
• Joseph Lacob, Partner, Kleiner Perkins
• Rodney Pearlman, Ph.D., CEO, Saegis Pharmaceuticals
• Roger Quy, Ph.D., General Partner, Technology Partners
• Gary Curtis, CEO, Concentric Medical
• Ryan Drant, General Partner, NEA

10:15 - 10:40 A.M.

Break

10:40 - 10:45 A.M.

Canyon Ranch Health Resort Giveaway
Donna Brammer, Sales Manager, Canyon Ranch

10:45 A.M. - 12:15 P.M.

Developing Interventions in Neurodegenerative Disease
Moderated by Richard Rudick, M.D., Director, Mellen Center, Department of Neurology; Chairman, Division of Clinical Research, Cleveland Clinic

• Sid Gilman, M.D., University Professor of Neurology, University of Michigan
• Paul Leber, M.D., Director, Neuro-Pharm Group, LLC
• Alastair JJ Wood, M.D., Managing Director, Symphony Capital

12:15 - 1:45 P.M.

Lunch - Founder's Ballroom
Implication of Care Pathways on Technology Adoption
Introduction by Sanjay Gupta, M.D., CNN, Senior Medical Correspondent

• David Holveck, Vice President, Corporate Development, Johnson & Johnson

Enterprise Ireland - Trip for 2 Giveaway
Sean McEllin, Regional Vice President, Enterprise Ireland

1:45 - 2:00 P.M.

Adjournment

2:15- 3:15 P.M.

Special Bonus Add-On

"Neurosciences and The Tour de France"

• Bob Roll, Author, OLN Correspondent & 4-Time Tour De France rider
• Jeff Spencer, DC, EFX, Inc.
• Anthony Miniaci, M.D., FRCS(C), Executive Director, Sports Health, Cleveland Clinic

MONDAY, OCTOBER 24, 2005

1:00 - 8:00 P.M.

Registration

2:00 P.M.

Exhibits Open - Light Refreshments
2nd and 3rd Floors

4:00 - 4:05 P.M.

A. Malachi Mixon III
Chairman & CEO, Invacare
Chairman of the Board of Trustees
The Cleveland Clinic

Welcome

4:05 - 4:15 P.M.

Delos M. Cosgrove, M.D.
CEO & President
The Cleveland Clinic
Innovation and The Cleveland Clinic

4:15 - 5:15 P.M.

Newt Gingrich
Former Speaker of the U.S. House of Representatives
The Promise and Challenge of Medical Innovation
Medical innovation will provide true added value, only if we can also transform our current health system. This talk proposes and defines an "intelligent health system" that improves health outcomes and the quality of life, leads to longer lives at lower costs, saves individuals, companies and governments billions of dollars.

5:15 - 6:05 P.M.

Michael E. Porter, Ph.D.
Bishop William Lawrence University Professor
Harvard Business School
Redefining healthcare: Creating Value-Based Competition on Results
To date, the participants in the healthcare system have competed at the wrong level - among health plans, networks, and hospitals - and on the wrong things. This presentation outlines a framework for creating healthcare competition based on patient value, which will require new strategies and operating practices for hospitals, physician practices and technology suppliers.

6:05 - 6:20 P.M.

Arthur D. Collins, Jr.
Chairman & CEO, Medtronic, Inc.
Chairman, AdvaMed
Looking Ahead in the Medical Technology Industry
Mr. Collins will provide his unique perspective, as Chairman of AdvaMed, on the challenges facing the orthopaedic industry.

7:00 - 10:30 P.M.

Opening Reception, Dinner and Entertainment
House of Blues

The Blues Brothers Band

TUESDAY, OCTOBER 25, 2005

6:30 A.M - 2:00 P.M.

Registration

6:30 - 7:30 A.M.

Continental Breakfast

7:00 A.M. - 7:00 P.M.

Exhibits Open
2nd and 3rd Floors

7:30 A.M.

Welcome

7:30 - 9:00 A.M.

Live Spine Surgeries
Moderated by Edward C. Benzel, M.D.
Chairman, Cleveland Clinic Spine Institute
The Cleveland Clinic

Innovation in Practice: New Minimally Invasive Spinal Surgeries

9:00 - 9:45 A.M.

Sir Christopher O'Donnell
Chief Executive
Smith & Nephew

Orthopaedic Innovation - A Global Perspective

Orthopaedic innovation arises from many sources - surgeons, engineers and countries around the world. Effective innovation requires high technology insights combined with effective economics to create both value and patient benefit. Learn about key international innovations in orthopaedics that deliver value to patients and to global healthcare systems.

9:45 - 10:30 A.M.

Break

10:30 - 11:15 A.M.

Stephen P. MacMillan
President & CEO
Stryker

Enhancing the Patient Experience via Innovation

A focus on the unique interconnectivity that surgeons, hospitals and medical device companies have in enhancing healthcare and meeting the expectations of patients. What is the value of medical technology and how it can be leveraged by all parties who are involved with today's healthcare system?

11:15 A.M. - 12:00 P.M.

Michael F. DeMane
Senior Vice President and Vice President Europe, Canada, Latin America and Emerging Markets
Medtronic
Spinal Innovations: Game-Changing Technologies

Compelling advances in the orthopaedic spinal market will enhance patient care in the coming years.

12:00 - 1:30 P.M.

Lunch
Michael J. Dormer
Worldwide Chairman, Medical Devices Group
Johnson & Johnson

History and Future of the Orthopaedics Marketplace
In the complex healthcare environment of the future, technology innovation alone will not drive standards of care. The orthopaedics industry will need to build expertise in public policy, outcomes research and patient advocacy in order to demonstrate the full value of its technologies in improving the standard of care and quality of life.

1:40- 3:10 P.M.

Moderated by Gordon R. Bell, M.D.
Vice Chairman, Cleveland Clinic Spine Institute,
Vice Chairman, Department of Orthopaedic Surgery
The Cleveland Clinic

• Edward C. Benzel, M.D., Chairman, Cleveland Clinic Spine Institute, The Cleveland Clinic
• Jeffrey R. Binder, President, Abbott Spine, Vice President, Abbott
• James M. Kuras, Senior Vice President & CTO, Axiomed
• Isador H. Lieberman, M.D., FRCS(C), Director of Minimally Invasive Surgery Center, The Cleveland Clinic
• Helmut D. Link, Managing Director, Waldemar Link, GmbH
• Eric D. Major, President & CEO, K2M
• Richard W. Mott, President & CEO, Kyphon
• Richard D. Randall, President & CEO, TranS1

New Spine Technologies
Leading innovators in spine technologies describe and debate opportunities and challenges of bringing new spine innovations that change the face of spinal surgery, from bench to bedside.

3:15 - 3:40 P.M.

Break

3:40- 4:40 P.M.

Moderated by Christopher M. Coburn
Executive Director, CCF Innovations
The Cleveland Clinic

• Paul E. DiCorleto, Ph.D., Chairman, Lerner Research Institute, The Cleveland Clinic
• Michael Fonstein, Ph.D., CEO & President, Cleveland BioLabs
• R. K. Khosla, CEO & President, Peritec Biosciences
• William C. Mulligan, Chairman, CCFI Industrial Advisory Board; Primus Venture Partners
• Mark R. Willig, President & CEO, PrognostiX
• Jay S. Yadav, Chairman, CCF Innovations; Cardiovascular Medicine, The Cleveland Clinic

Commercializing Cleveland Clinic Technology
The Cleveland Clinic has a long history of innovation with a growing portfolio of market-important IP. This panel will describe the importance of commercialization to the Clinic, the opportunity for outside investors, the quality and breadth of research at the Clinic, and how the commercialization system integrates researchers, innovators, investors, and patient needs.

4:40 - 6:10 P.M.

Moderated by Jonathan L. Schaffer, M.D.
Advanced Orthopaedic Technology Group
Orthopaedic Research Center
The Cleveland Clinic

• Sheryl L. Conley, President, Global Products Group, Zimmer
• Fred B. Dinger, President & CEO, OsteoBiologics, Inc.
• Steven W. Ek, Executive Vice President and Chief Operating Officer, Arthrosurface
• Gary D. Henley, President, Orthofix, Inc.
• Joseph P. Iannotti, M.D., Ph.D., Chairman, Department of Orthopaedic Surgery, The Cleveland Clinic
• Viktor E. Krebs, M.D., Head, Section of Adult Reconstructive Surgery, Department of Orthopaedic Surgery, The Cleveland Clinic
• Dane A. Miller, Ph.D., President & CEO, Biomet
• Michael P. Mogul, President, Stryker Orthopaedics

New Joint Technologies
This panel of leading innovators and joint surgeons will present and debate what's new and hot in joint technologies today, what will we see over the next five to ten years, and the challenges to making these innovations a successful reality for companies, hospitals and society.

6:10 - 7:00 P.M.

Welcome Reception

7:00 P.M.

Dinner
Sponsored by Norman Noble/Electrolizing
Stephen J. Ubl
President & CEO
AdvaMed
Federal Policy Trends and Their Impact on the Orthopaedic Industry

An update on the national dynamics, trends and issues around orthopaedic innovation and medical devices regulation: product approval and clearance, reimbursement, and access to international markets.
Scott Gottlieb, M.D.
Deputy Commissioner for Medical and Scientific Affairs
U.S. Food and Drug Administration

FDA Commissioner's Office Strategies to Speed the Flow of Safe and Effective Innovations in the U.S.
What new strategies will the FDA use to improve the speed and lower the cost to get higher quality innovations from bench to bedside in a more timely and cost-effective manner? What new post-market regulations or changes can we expect from the FDA?

WEDNESDAY, OCTOBER 26, 2005

6:30 - 9:00 A.M.

Registration

6:30 - 7:30 A.M.

Continental Breakfast

7:00 A.M. - 2:00 P.M.

Exhibits Open
2nd and 3rd Floors

7:30 - 9:00 A.M.

Live Joint Surgeries

Moderated by Peter J. Evans, M.D., Ph.D.
Head, Section of Hand & Upper Extremity Surgery
Department of Orthopaedic Surgery
The Cleveland Clinic

Innovation in Practice: New Minimally Invasive Joint Surgeries

9:00- 10:45 A.M.

Moderated by Harry T. Rein
General Partner
Foundation Medical Partners

• Steven J. Healy, President & CEO, Disc Dynamics
• Alan L. Kaganov, Sc.D., Partner, U.S. Venture Partners
• Mark D. LoGuidice, Chairman & CEO, Spine Wave
• Kevin K. Sidow, President & CEO, St. Francis Medical Technologies
• David W. Stassen, Managing Director, Split Rock Partners
• Karen D. Talmadge, Ph.D., Co-Founder, CSO & EVP, Kyphon
• Elizabeth H. Weatherman, Partner, Warburg Pincus

Venture Capital and Orthopaedics
Venture Capital is a critical resource for bringing orthopaedic innovations from bench to bedside. healthcare industry venture capitalists discuss their rationale for backing innovative firms, while company executives explain the unique aspects of venture capital and commercialization in the orthopaedics market, including special challenges and new financing approaches.

10:45- 11:15 A.M.

Break

11:15 A.M. - 12:30 P.M.

Moderated by Michael T. Modic, M.D.
Chairman, Division of Radiology
The Cleveland Clinic

• C. Martin Harris, M.D., Chief Information Officer, The Cleveland Clinic
• Jeffrey D. Miller, Vice President of Health and Life Sciences Industries, Hewlett-Packard Company
• Thomas J. Miller, President, Siemens Medical Solutions Health Services
• Patricia Perry, General Manager, Digital Health Group, Intel
• F. David Rollo, M.D., Ph.D., Chief Medical Officer, Philips Medical Systems

Comprehensive System Integration vs. Best in Breed
Which goal is more productive and effective: system integration or best in breed innovation?

12:30- 1:50 P.M.

Lunch
Joseph M. Hogan
President & CEO
GE Healthcare
Orthopaedic Challenges and Opportunities:
Perspectives from the Fortune 5
As a Fortune 5 employer, a leading global supplier of medical devices and a player in multiple industries that are converging to provide even higher quality orthopaedic medical innovations, GE is in a prime position to understand and give perspective on changing market demand, global regulatory and legal requirements and convergence opportunities.

1:50- 2:00 P.M.

Jay S. Yadav, M.D.
Chairman, CCF Innovations
Cardiovascular Medicine
The Cleveland Clinic

Wrap Up

MONDAY, OCTOBER 18, 2004

1:00 - 9:00 P.M.

Registration

4:00 - 4:15 P.M.

Welcome

A. Malachi Mixon III
Chairman and CEO, Invacare;
Chairman of the Board of Trustees, The Cleveland Clinic Foundation

Delos M. Cosgrove, M.D.
CEO and President, The Cleveland Clinic

4:15 - 5:15 P.M.

The AMGEN Experience

Kevin Sharer
Chairman and CEO, AMGEN

5:15 - 6:15 P.M.

Taxus: How do we get so lucky?
The Harder We Worked, the Luckier We Got!

James R. Tobin, Chairman and CEO, Boston Scientific The unique challenges associated with the development of combination drug/device technologies. The impact of approach, infrastructure and mind set. Owning the organization strategy of ‘not being first but being best'.

6:30 - 10:30 P.M.

Opening Reception, Dinner and Entertainment
Watch the Cleveland Cavaliers play the New Jersey Nets at Gund Arena, followed by a reception with Cavaliers General Manager Jim Paxson and select players and staff.

TUESDAY, OCTOBER 19, 2004

6:30 A.M - 2:00 P.M.

Registration

7:00 - 8:00 A.M.

Continental Breakfast

8:00 - 8:20 A.M.

The Honorable Bob Taft
Governor of Ohio

State of Cardiology
Eric J. Topol, M.D., Provost and Chief Academic Officer; Chairman, Department of Cardiovascular Medicine, The Cleveland Clinic
This address includes critical trends in cardiology, new therapies, diagnostics and clinical approaches; and their impact on per-patient expenses.

8:20 - 9:50 A.M.

Cardiovascular Innovation in Action
Panel moderated by Eric J. Topol, M.D.:
Marc S. Penn, M.D., Ph.D., Director, Cardiac Intensive Care Unit, CCF
Patrick L. Whitlow, M.D., Cardiovascular Medicine, CCF
Ferolyn Powell, CEO, Evalve
Bruce L. Wilkoff, M.D., Cardiovascular Medicine, CCF
Michael J. Coyle, President, St. Jude Medical CRMD
Mario J. Garcia, M.D., Cardiovascular Medicine, CCF

9:50 - 10:20 A.M.

Break

10:20 - 11:00 A.M.

A Case Study in Cardiovascular Therapy

Steve S. Nissen, M.D., Cardiovascular Medicine, CCF
Roger S. Newton, Ph.D., CEO, Esperion

11:00 - 11:50 A.M.

Speeding Cardiovascular Innovation in an Uncertain Environment

Guy J. Lebeau M.D., Company Group Chairman, Cordis
Jay S. Yadav, M.D., Department of Cardiovascular Medicine, The Cleveland Clinic Foundation

12:00 - 1:15 P.M.

Lunch

The Honorable Jane L. Campbell, Mayor
The City of Cleveland, Ohio

A Policy Environment that Encourages Medical Innovation
Ronald W. Dollens, President and CEO, Guidant

How do today's health policies both encourage and discourage medical innovation.

1:15 - 2:10 P.M.

Lessons in Innovation: A Case Study in Heart Failure

William A. Hawkins III, President and COO, Medtronic

2:10 - 2:25 P.M.

The State of Cardiac Surgery

Bruce W. Lytle, M.D., Chairman, Department of Thoracic & Cardiovascular Surgery, The Cleveland Clinic

2:25 - 3:25 P.M.

Surgical Innovation in Action

Panel moderated by Bruce W. Lytle, M.D.:

Marc Gillinov, M.D., Thoracic and Cardiovascular Surgery, CCF
Dave Drachman, President and CEO, AtriCure
Nick G. Smedira, M.D., Thoracic and Cardiovascular Surgery, CCF
P. Richard Lunsford, President and CEO, Acorn Cardiovascular
Roy Greenberg, M.D., Vascular Surgery, CCF
Charles McIntosh, M.D., Ph.D., CTO, Cook Group

3:25 - 3:55 P.M.

Break

3:55 - 4:30 P.M.

The Biomedical Century: New Technology, New Evidence, New Costs
Mark B. McClellan, M.D., Ph.D. , Administrator, Center for Medicare and Medicaid Services, Department of Health and Human Services

New scientific approaches allow for more individualized, effective treatments based on a fundamental understanding of how diseases affect individual patients. The challenge of making healthcare decisions based on sound evidence of benefits and costs for individual patients may determine whether we realize the potential for better medical care in the 21st century.

4:30 - 5:10 P.M.

Cardiovascular Innovation in International Markets: Challenges and Opportunities
Michael A. Mussallem, Chairman and CEO, Edwards Lifesciences Corporation
While cardiovascular disease is projected to remain the leading cause of death in the world for decades to come, investment in cardiovascular care varies widely around the globe. Mr. Mussallem will discuss the environmental and cultural factors required for successful cardiovascular innovation, as well as the potential for disruptive technologies to serve the growing, high-need patient population.

5:10 - 5:50 P.M.

Fostering Innovation Through Integration

Robert D. Walter, Founder, Chairman and CEO, Cardinal Health

The pace of innovation and need to continually serve customers is unyielding in the $4 trillion global healthcare market. Cardinal Health has quietly built its business by fostering a culture that thrives on the rate of change in healthcare, rapidly adding new products and services, acquiring new capabilities and innovating in strategic areas of process, technology and service delivery. In his presentation, Robert D. Walter provides examples and discusses the lessons he has learned that have enabled Cardinal Health to become the preeminent ‘healthcare to healthcare' provider in this vast marketplace.

6:00 - 7:00 P.M.

Welcome Reception
Hosted by Squire, Sanders & Dempsey, LLP

7:00 P.M.

Dinner

Remaking healthcare Innovation
Clayton M. Christensen, Robert and Jane Cizik Professor of Business Administration, Harvard Business School

WEDNESDAY, OCTOBER 20, 2004

6:30 - 9:00 A.M.

Registration

6:30 - 7:30 A.M.

Continental Breakfast

7:30 - 9:00 A.M.

Live Surgery Moderated by Kenneth Ouriel, M.D.,
Chairman, Division of Surgery, The Cleveland Clinic

Innovation in Practice: Side-by-Side Comparison of Traditional Surgeries with New Minimally Invasive Counterparts

9:00 - 9:45 A.M.

Juan Enriquez
Chairman and CEO, Biotechonomy

9:45 - 10:15 A.M.

Break

10:15 - 11:00 A.M.

Success in the Midst of Savage Competition

Timothy M. Ring, President and CEO, C.R. Bard

11:00 - 12:00 P.M.

The Challenge in the Commercialization of Cardiovascular Technology
Panel moderated by Harry T. Rein, General Partner
Foundation Medical Partners and includes:

Olav B. Bergheim, General Partner, Domain Associates
Jim Broderick, M.D., General Partner, Morgenthaler Ventures
Mark Maciejewski, CEO, Symphony Medical
Jim M. Sweeney, CEO, Cardionet
Ken Charhut, President and CEO, Orqis

12:15 - 1:15 P.M.

Lunch

FDA's Initiatives to Stimulate Medical Innovation
Lester M. Crawford, D.V.M., Ph.D. Acting Commissioner U.S. Food and Drug Administration
Dr. Crawford addresses the agency's recent efforts to encourage new drug and device development and manufacturing through regulation reform and by identifying and addressing hazards that cause the failure of candidate drugs/devices to demonstrate safety and effectiveness.

1:15 - 2:00 P.M.

New Imaging Technologies and Impact in Underlying Economics

Erich R. Reinhardt, D.Eng.
Group President and CEO, Siemens Medical Solutions
Many innovative technologies, for example CT and MR, have emerged in the past few decades. These technologies have fundamentally changed medical diagnostics and helped to increase the quality of healthcare and reduce its cost.
Mr. Reinhardt will focus on the potential for innovation in diagnostic and therapeutic technologies to continue to improve healthcare efficiency, and especially address the promising role of molecular medicine.

2:00 - 2:45 P.M.

Regulatory Approval: A Case Study with an Historical Perspective

Col. William C. DeVries, M.D.
Walter Reed Army Medical Center

3:00 - 3:30 P.M.

Wrap Up

TUESDAY, OCTOBER 7, 2003

7:00 - 8:00 A.M.

Registration and Continental Breakfast

8:00 - 8:45 A.M.

Welcome to The Cleveland Clinic Foundation and the City of Cleveland A. Malachi Mixon III
Chairman and CEO, Invacare;
Chairman of the Board of Trustees, The Cleveland Clinic Foundation
Floyd D. Loop, M.D.
Chairman and CEO, The Cleveland Clinic Foundation
The Honorable Jane L. Campbell, Mayor
City of Cleveland, Ohio

8:45 - 9:45 A.M.

The Human Genome:
From Discovery to Therapies
Francis S. Collins, M.D., Ph.D.
Director, National Human Genome Research Institute
Introduction by Delos M. Cosgrove, M.D.
Chairman, Department of Thoracic & Cardiovascular Surgery
The Cleveland Clinic Foundation

9:45 - 10:05 A.M.

Break

10:05 - 11:30 A.M.

Innovation and Integration:
Scientific and Technological Advances Redefining Medicine
Richard L. Marrapese and Scott W. Morrison
Partners, Ernst and Young Healthcare and Life Sciences Practices
Introduction by Michael P. O'Boyle
Chief Financial Officer, The Cleveland Clinic Foundation

11:30 - 12:50 P.M.

Luncheon
The Honorable Bob Taft
Governor of Ohio Making Medical Innovation Available:
Patient Access to New Technology
Arthur D. Collins, Jr.
Chairman and CEO, Medtronic
Introduction by Joseph F. Hahn, M.D.
Chairman, Division of Surgery, The Cleveland Clinic Foundation

1:00 - 2:00 P.M.

The Need for Speed:
Bench to Boardroom to Bedside
Mark B. McClellan, M.D., Ph.D.
Commissioner of the U.S. Food and Drug Administration Introduction by Eric J. Topol, M.D.
Provost and Chief Academic Officer, The Cleveland Clinic Foundation

2:00 - 2:15 P.M.

Break

2:15 - 3:45 P.M.

Ensuring Availability to All Who Need It:
What Can Industry Leaders Do?
Moderator:
Pamela G. Bailey
President, AdvaMed
Panel:
Dane A. Miller, Ph.D.
President and CEO, Biomet
Michael A. Mussallem
Chairman and CEO, Edwards Lifesciences
Timothy M. Ring
Chairman and CEO, C.R. Bard

3:45 - 4:35 P.M.

Financial Relationships Among Industry, Scientific Investigators,
And Academic Institutions
John P. Wareham
Chairman, President and CEO, Beckman Coulter
Introduction by Robert Kay, M.D.
Vice Chairman, Board of Governors, The Cleveland Clinic Foundation

4:35 - 5:00 P.M.

Break

5:00 - 6:00 P.M.

Advancing to the Next Frontier of Medical Innovation:
Moving Beyond Price
Miles D. White
Chairman and CEO, Abbott Laboratories
Introduction by Kenneth Ouriel, M.D.
Chairman, Department of Vascular Surgery, The Cleveland Clinic Foundation

6:30 - 7:00 P.M.

Buses Depart for Dinner Reception at Rock & Roll Hall of Fame

7:00 - 11:00 P.M.

Rock This Town: Dinner Reception at the Rock & Roll Hall of Fame Live Music
Return transportation will begin at 8:30 pm

WEDNESDAY, OCTOBER 8, 2003

6:30 - 7:30 A.M.

Continental Breakfast

7:30 - 8:30 A.M.

Medical Innovation In Action:
Live Cardiac Valvuloplasty Surgery
(interactive video broadcast live from the operating room) Delos M. Cosgrove, M.D.
Chairman, Department of Thoracic & Cardiovascular Surgery
The Cleveland Clinic Foundation

8:30 - 9:15 A.M.

Innovation: A Pillar of Operational Excellence
Harry M. Kraemer, Jr.
Chairman and CEO, Baxter
Introduction by Martin J. Schreiber, Jr., M.D.
Board of Governors, The Cleveland Clinic Foundation

9:15 - 10:00 A.M.

Responding to the World's Increasing Demand for Biomedical Innovation
John W. Brown
Chairman and CEO, Stryker Corporation
Introduction by Peter R. Cavanagh, Ph.D.
Chairman, Department of Biomedical Engineering, The Cleveland Clinic Foundation

10:00 - 10:20 A.M.

Break

10:20 - 11:30 A.M.

Increasing the Sense of Urgency
Moderator:
Delos M. Cosgrove, M.D.
Chairman, Department of Thoracic & Cardiovascular Surgery
The Cleveland Clinic Foundation Panel:
Thomas J. Fogarty, M.D.
Co-founder and Senior Partner, Three Arch Partners
Jack W. Lasersohn
General Partner, The Vertical Group
Edward J. Ludwig
Chairman, President and CEO, BD

11:30 - 12:15 P.M.

Coming Together as an Industry in the Battle Against
New Infectious Diseases and Bio-terrorism
Les C. Vinney
President and CEO, STERIS Introduction by Steven M. Gordon, M.D.
Department of Infectious Diseases, The Cleveland Clinic Foundation

12:15 - 2:00 P.M.

Luncheon
The Future of Biomedical Innovation
William C. Weldon
Chairman and CEO, Johnson & Johnson Introduction by Jeffrey L. Ponsky, M.D.
Vice Chairman, Division of Education
Director of Graduate Medical Education and Department of General Surgery, The Cleveland Clinic Foundation

2:00 - 3:15 P.M.

Personalized Medicine Promises to be Safer and More Effective...
but Raises Difficult Economic and Ethical Questions
Moderator:
Eric J. Topol, M.D.
Provost and Chief Academic Officer, The Cleveland Clinic Foundation Panel:
C. Martin Harris, M.D.
Chief Information Officer, The Cleveland Clinic Foundation Caroline A. Kovac, Ph.D.
General Manager, IBM Life Sciences Raymond P. Warrell, Jr., M.D.
Chairman and CEO, Genta

3:15 - 3:35 P.M.

Break

3:35 - 4:30 P.M.

Innovation Also Requires Changes in the Healthcare Delivery System Ron Winslow
Health Editor, Wall Street Journal Introduction by Frank L. Lordeman
Chief Operating Officer, The Cleveland Clinic Foundation

4:30 - 6:00 P.M.

Cocktails and Convergence

6:00 - 8:30 P.M.

Dinner
Medicare Policy and New Technology
Thomas A. Scully
Administrator, Centers for Medicare & Medicaid Services,
U.S. Department of Health and Human Services Introduction by Floyd D. Loop, M.D.
CEO, The Cleveland Clinic Foundation

THURSDAY, OCTOBER 9, 2003

7:00 - 8:00 A.M.

Continental Breakfast

8:00 - 9:00 A.M.

Convergence with a Purpose:
Meet, Connect, Dialog, Unite, Act
Erich R. Reinhardt, D.Eng.
President and CEO, Siemens Medical Solutions Introduction by Michael T. Modic, M.D.
Chairman, Division of Radiology, The Cleveland Clinic Foundation

9:00 - 10:30 A.M.

The Role Of Venture Capital In Improving America's Health
Moderator:
Keith M. Kerman, M.D.
Managing Director, Primus Venture Partners Panel:
Samuel D. Colella
Co-founder and Managing Director, Versant Ventures Brian H. Dovey
General Partner, Domain Associates Bill R. Sanford
Executive Founder and Retired Chairman and CEO, STERIS;
Chairman, BioEnterprise Harry T. Rein
Senior Advisor, Foundation Medical Partners

10:30 - 11:00 A.M.

Break

11:00 - 12:00 P.M.

Innovation to Commercialization
Panel:
Jouko Karvinen
President and CEO, Philips Medical Systems Carl F. Kohrt, Ph.D.
President and CEO, Battelle Introductions by Paul E. DiCorleto, Ph.D.
Chairman, Lerner Research Institute, The Cleveland Clinic Foundation

12:00 - 12:30 P.M.

Conference Summary
The Perspectives of an Industry Statesman
George N. Hatsopoulos, Ph.D.
Chairman, Founder and CEO, Pharos;
Founder and CEO Emeritus, Thermo Electron Introduction by Christopher M. Coburn
Executive Director, CCF Innovations
The Cleveland Clinic Foundation

12:30 P.M.

Conference Closing
Joseph F. Hahn, M.D.
Chairman, CCF Innovations
Chairman, Division of Surgery, The Cleveland Clinic Foundation