2012 Medical Innovation Summit

21st Century Orthopaedics: Hands-On Perspectives from Clinical Leaders
Two renowned orthopaedists provide their unique outlook on the strengths and challenges in the orthopaedic field and how the climate for innovation holds the potential for extraordinary change

Joseph Iannotti, MD, PhD, Chair, Orthopaedic and Rheumatologic Institute, Cleveland Clinic
Richard Parker, MD, Chair, Orthopaedic Surgery, Cleveland Clinic

The State of Healthcare Innovation
Leaders of some of the most influential organizations in healthcare provide their unique outlook on the challenges facing the healthcare industry, where we are and where we're heading.

 Moderator: Mary Jordan, Editor, Washington Post Live

David Meeker, MD, President and Chief Executive Officer, Genzyme
Robert Moritz, Chairman and Senior Partner, US Firm of PricewaterhouseCoopers LLP
Harry Rein, General Partner, Foundation Medical Partners
Kevin Sharer, Chairman, Amgen

Returning to Work: Repairing Athletic Injuries Over the Decades
A lively discussion with world-class athletes whose stellar careers were derailed by injury and how, in some cases, innovative orthopaedic procedures restored them to competition

Moderator: Rowdy Gaines, Three-time Olympic Gold Medalist and Member of the International Swimming Hall of Fame

Shannon Bahrke Happe, Three-time Olympic Skier & World Champion
Zydrunas Ilgauskas, Retired NBA All-Star and All-Rookie MVP
Michael McBrayer, Senior Vice President, DJO Global
Richard Parker, MD
Mark Schickendantz, MD, Director, Sports Medicine, Cleveland Clinic
David Scott, U.S. Triathlete and Six-Time Ironman Triathlon World Champion

Orthopaedics: Bull or Bear Market?
Uniformly optimistic or uniformly pessimistic? Six of the market's smartest thinkers debate the prospects for orthopaedic innovation in this challenging healthcare climate

Moderator: Matthew Herper, Writer, Forbes

James Capretta, Fellow, Ethics and Public Policy Center
David Cutler, PhD, Otto Eckstein Professor of Applied Economics, Harvard University
Brian Donley, MD, President, Lutheran Hospital
Viktor Krebs, MD, Orthopaedic Surgery, Cleveland Clinic
Jeff Shuren, MD, Director, Center for Devices and Radiological Health, Food and Drug Administration

Swifter, Higher, Stronger
The world was riveted by the London Olympic Games and the thousands of athletes pushing their bodies to new thresholds of speed, endurance, and stress. There were more than 1,000 U.S. Olympians, but for the first time in U.S. Olympic history, there were more female athletes than males. The average age of all Olympians was 26, but 187 competitors were 40 and older and 137 were younger than 15. Dr. Schamasch, one of the world’s leading sports medicine experts, along with two Cleveland Clinic pediatric and female sports medicine physicians, share their perspectives on the
Moderator: Scott Simon

Susan Joy, MD, Orthopaedic Surgery, Cleveland Clinic
Paul Saluan, MD, Orthopaedic Surgery, Cleveland Clinic
Patrick Schamasch, MD, Medical & Scientific Director, International Olympic Committee

Great Expectations: The Future Wave of Orthopaedic Innovation
Leading orthopaedic experts review the greatest scientific advances and technologies that have dramatically changed the prevention, diagnosis, treatment, and rehabilitation of orthopedic disorders over the past two decades. They will also discuss the next wave of innovation expected in the coming years that will allow doctors to better treat their patients. The contrast between technologies of today and the projected medical miracles will highlight the importance of continued innovation.

Moderator: David Cassak, Elsevier Business Intelligence

Peter Brooks, MD, Orthopaedic Surgery, Cleveland Clinic
Joe Darling, President, ConMed Linvatec
David Jensen, President, Acumed
Jeffrey MCaulley, President, Reconstruction, Zimmer
Richard Parker, MD

Joint Replacement State of the Art: Facts, Fictions, Futures
Leaders of the major orthopaedic device companies review the market dynamics of new technologies leading to more patients getting hip and knee procedures at younger ages and its implication on healthcare. A look at all of the materials being tested and used, computer-enhanced design for orthopaedic accuracy of each replacement and reasons for the move to overseas testing of new products.

Moderator: David Cassak, Elsevier Business Intelligence

Naseem Amin, Chief Scientific Officer, Advanced Medical Devices, Smith & Nephew
Andrew Ekdahl, Worldwide President, DePuy Reconstruction
Maurice Ferré, MD, Chief Executive Officer, MAKO Surgical
Mark Froimson, MD, President, Euclid Hospital
Gregory Gilot, MD, Chair, Orthopaedic Surgery, Cleveland Clinic Weston
William Petty, MD, Chief Executive Officer, Exactech

Lunch: Founders Ballroom

Welcome: Cleveland Mayor Frank Jackson

Fireside chat with
Omar Ishrak, PhD, Chief Executive Officer, Medtronic

The Chief Executive Officer of one of the world’s premier medical innovation companies will discuss his perspectives on the global healthcare environment. In his remarks and in a one-on-one conversation with National Public Radio’s Scott Simon, Mr. Ishrak will share his perspectives on significant global opportunities, overcoming barriers to access, and innovative approaches to addressing worldwide healthcare needs.

Moderated by: Scott Simon

Investing in Orthopaedic Technologies
Join leading experts to discuss investment perspectives in orthopaedics.

Moderator: Tom Salemi, Elsevier Business Intelligence

Teo Forcht Dagi, MD, HLM Ventures
Doug Kelly, MD, General Partner, Alloy Ventures
Justin Klein, Partner, New Enterprise Associates
David Roman, Vice President, Global Investment Research, Medical Devices, Goldman Sachs Group
Jonathan Schaffer, MD, Staff, Orthopaedic Surgery, Cleveland Clinic
Anthony Viscogliosi, Chairman and Chief Executive Officer, Small Bone Innovations

CEO One-on-One

Moderator: David Ewing Duncan

Jeffrey Binder, Chief Executive Officer, Biomet

In the relatively short time since its founding in 1977, Biomet has grown to be an international leader in orthopaedic technologies with $2.5 billion in annual sales in approximately 90 countries. Mr. Binder has been a leading voice in advocating joint replacement procedures as a form of preventive care to prevent the personal pain and high health costs associated with osteoarthritis. Mr. Binder will share his perspectives on
the future of orthopaedics in a conversation with award-winning journalist David Ewing Duncan.

Break

Raffle Drawing: First of Two. One Medical Innovation Summit attendee will be selected at random to win a trip for two to Ireland. Must be present to win! Cleveland Clinic Employees are not eligible.

Concurrent Sessions

- IBM Watson and the Future of Medicine
In the months since Watson's brief TV career, Dr. David Ferrucci and his team of researchers have been working to enhance the capabilities of Watson's Deep Question Answering technology for the area of medicine. Watson is moving beyond a single-sentence question to allow for analyzing rich case scenarios considering many independent factors. Dr. Ferrucci will demonstrate a new application that uses multi-step inference chaining, evidence building and collaborative dialog to deliver powerful decision support.

Moderator: Martin Harris, MD, Chief Information Officer, Cleveland Clinic

Mike Barborak, Manager, Natural Language Engineering and Frameworks, IBM
Eric Brown, PhD, Research Staff Member and Senior Manager, IBM Research
David Ferrucci, PhD, Vice President and Principal Investigator, DeepQA/Watson Project, IBM Research
Eric Jelovsek, MD, Education Institute, Cleveland Clinic
Neil Mehta, MD, Education Institute, Cleveland Clinic
James Stoller, MD, Chair, Education Institute, Cleveland Clinic
James Young, MD, Executive Dean, Education Institute, Cleveland Clinic

- Inflammation & Environment in Orthopaedic Disease
The role of inflammation on cartilage damage in arthritis and orthopaedic disease had been unclear, but significant progress has been made in recent years to assess its impact. Experts describe molecular pathways, drug therapies, and other research avenues that are leading to new treatment options.

Moderator: Pat Fortune, PhD, Senior General Manager, Cleveland Clinic Innovations

Abby Abelson, MD, Chair, Rheumatologic and Immunologic Disease, Cleveland Clinic
David Ewing Duncan
Jeff Hersh, MD, PhD, Senior Medical Director, GE Healthcare
Elaine Husni, MD, Staff, Rheumatologic and Immunologic Disease

- Regenerative Medicine: Overcoming Challenges to Replace, Repair, or Promote Tissue Regeneration
Corporate leaders of leading edge companies provide their unique insights on how regenerative medicine will change how orthopaedic injuries are treated.

Moderator: Tom Salemi

Frank Barry, PhD, Scientific Director Remedi
Dan Grande, PhD, Orthopaedic Research, North-Shore Long Island Jewish Health System
George Muschler, MD, Staff, Orthopaedic Surgery, Cleveland Clinic
Mitch Seyedin, PhD, Chief Executive Officer, ISTO
Maria Siemionow, MD, PhD, DSc, Plastic Surgery, Cleveland Clinic
Bruce Stroever, President and Chief Executive Officer, Musculoskeletal Transplant Foundation
Laurence Tarrant, PhD, Chief Scientific Officer and Founder, Histogenics

- Innovating on a Deadline: Breakthrough Orthopaedic Technology in a Short-Cycle Environment
Experts describe tactics needed for success in today's market, including being prepared to meet tighter FDA approval regulations, showing a differentiation from what already exists, having surgeons on board, addressing the economics of orthopedic surgery, and showing advantages for patient care.

Moderator: David Cassak

Wael Barsoum, MD, Orthopaedics, Cleveland Clinic
Kenneth Greene, MD, Orthopaedic Surgery, Cleveland Clinic
Clyde Pratt, Chief Executive Officer, Kinamed, Inc.
Brady Shirley, President and Chief Executive Officer, Innovative Medical Device Solutions
Dennis Stripe, Chief Executive Officer, OrthoHelix Surgical Designs, Inc.
Richard Wesorick, Partner, Tarolli, Sundheim, Covell & Tummino LLP

CEO One-on-One
Moderator: David Ewing Duncan, Author & Journalist

David Dvorak, Chief Executive Officer, Zimmer

New Imaging Modalities shaping Orthopaedics

Moderator: David Cassak

Tom Gentile, President & Chief Executive Officer, Healthcare Systems, General Electric
Joseph Iannotti, MD, PhD
Tsuneo Imai, Senior Director and General Manager, Healthcare Solutions, Canon
Robert Morocco, Chief Executive Officer, Orthoscan
Greg Sorensen, MD, Chief Executive Officer, Siemens Healthcare North America
Hamid Tabatabaie, Chief Executive Officer, lifeIMAGE
Luc Thijs, President, AGFA Healthcare
Carl Winalski, MD, Diagnostic Radiology, Cleveland Clinic

Unlocking Value from Big Data

Moderator: David Ewing Duncan

Ashley Dombkowski, PhD, Chief Business Officer, 23 and me
David Ferrucci, PhD, Group Manager, Semantic Analysis and Integration, IBM Research
Jeffrey Gruen, MD, Partner, PricewaterhouseCoopers
Martin Harris, MD
Steve McHale, Chief Executive Officer, Explorys
Mark Smith, MD, Director, MedStar Institute for Innovation

Raffle Drawing: Second Drawing. One Medical Innovation Summit attendee will be selected at random to win a trip for two to Ireland. Must be present to win! Cleveland Clinic Employees are not eligible.

Lunch: Founders Ballroom

CEO One-on-One
Jeff Smisek, President and Chief Executive Officer, United Airlines

Moderator: Diane Eastabrook, Correspondent, Nightly Business Report